LRP8 ELISA Kit for Chicken(Gallus gallus) | EIAab.comLRP8 ELISA Kit for Chicken(Gallus gallus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > LRP8(Gene name) > Chicken

LRP8 (Gene name),

Low-density lipoprotein receptor-related protein 8 (Protein name ), LRP8_CHICK from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

LRP8(LR8B);

Protein name:

Low-density lipoprotein receptor-related protein 8(LRP-8);

Alternative:

Protein LR8B;Apolipoprotein E receptor 2;

Organism:

Chicken (Gallus gallus).

General Annotation

Sub Unit:

Reelin associates with two or more receptor molecules. Interacts with DAB1 and JNK-interacting proteins.

Function:

Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. Also binds alpha2-macroglobulin. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

917

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

917:

HVYPARVALS | LEDDGLP

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

Q98931

UniGene:

Gga.3461

SMR:

Q98931

Pfam:

PF12662

Pfam:

PF00057

KEGG:

gga:396102

Uniprot:

Q98931

FOR

ELISA Kit for Chicken LRP-8

Cat.:

E10006h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Chicken LRP-8

MSDS:

Please sign in first.

ELISA Kit for Chicken LRP-8

Cat.:

E10006m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Chicken LRP-8

MSDS:

Please sign in first.

CLIA Kit for Chicken LRP-8

Cat.:

U10006h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Chicken LRP-8

Cat.:

U10006m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Chicken LRP-8

Cat.:

P10006Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Chicken LRP-8

Monoclonal Antibody for Chicken LRP-8

Protein for Chicken LRP-8

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A new LDL receptor homologue with 8 ligand binding repeats in brain of chicken and mouse."
Novak S. , Hiesberger T. , Schneider W.J. , Nimpf J.
J. Biol. Chem.271:11732-11736(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain: White leghorn.
tissue: Brain.
2.

"Alternative splicing in the ligand binding domain of mouse ApoE receptor-2 produces receptor variants binding reelin but not alpha2-macroglobulin."
Brandes C. , Kahr L. , Stockinger W. , Hiesberger T. , Schneider W.J. , Nimpf J.
J. Biol. Chem.276:22160-22169(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING;INTERACTION WITH ALPHA2-MACROGLOBULIN

Product Feedback Wall

* Email:
*Comments: