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Index > Protein center > MAPK14(Gene name) > Dog
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  • MAPK14 (Gene name),
  • Mitogen-activated protein kinase 14 (Protein name ),  MK14_CANFA from NCBI database.
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  • Antigen Annotation
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  • Gene name:
    MAPK14(CSBP1;CSBP2);
    Protein name:
    Mitogen-activated protein kinase 14(MAP kinase 14;MAPK 14);
    Alternative:
    Mitogen-activated protein kinase p38 alpha(MAP kinase p38 alpha);
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Binds to a kinase interaction motif within the protein tyrosine phosphatase, PTPRR. This interaction retains MAPK14 in the cytoplasm and prevents nuclear accumulation. Interacts with FAM48A, SPAG9 and NP60.
    Function:
    Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO during hypoxic stress.
    Subcellular Location:
    Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    360
    Sequence:
    50:
    MSQERPTFYR | QELNKTIWEV | PERYQNLSPV | GSGAYGSVCA | AFDTKTGLRV | 
    100:
    AVKKLSRPFQ | SIIHAKRTYR | ELRLLKHMKH | ENVIGLLDVF | TPARSLEEFN | 
    150:
    DVYLVTHLMG | ADLNNIVKCQ | KLTDDHVQFL | IYQILRGLKY | IHSADIIHRD | 
    200:
    LKPSNLAVNE | DCELKILDFG | LARHTDDEMT | GYVATRWYRA | PEIMLNWMHY | 
    250:
    NQTVDIWSVG | CIMAELLTGR | TLFPGTDHID | QLKLILRLVG | TPGADLLKKI | 
    300:
    SSESARNYIQ | SLTQMPKMNF | ANVFIGANPL | AVDLLEKMLV | LDSDKRITAA | 
    350:
    QALAHAYFAQ | YHDPDDEPVA | DPYDQSFESR | DLLIDEWKSL | TYDEVVSFVP | 
    360:
    PPLDQEEMES | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Dog MAP kinase 14
    Cat.:
    E9114h
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    Packing:
    96T
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    ELISA Kit for Dog MAP kinase 14
    MSDS:
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    ELISA Kit for Dog MAP kinase 14
    Cat.:
    E9114m
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    Packing:
    96T
    ELISA Kit for Dog MAP kinase 14
    Cat.:
    E9114r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog MAP kinase 14
    MSDS:
    Please sign in first.
    CLIA Kit for Dog MAP kinase 14
    Cat.:
    U9114h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Dog MAP kinase 14
    Cat.:
    U9114m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog MAP kinase 14
    Cat.:
    U9114r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Dog MAP kinase 14
    Cat.:
    P9114Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog MAP kinase 14
    Cat.:
    P9114Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog MAP kinase 14
    Polyclonal Antibody for Dog MAP kinase 14
    Monoclonal Antibody for Dog MAP kinase 14
    Monoclonal Antibody for Dog MAP kinase 14
    Monoclonal Antibody for Dog MAP kinase 14
    Monoclonal Antibody for Dog MAP kinase 14
    Protein for Dog MAP kinase 14
    Protein for Dog MAP kinase 14
    Protein for Dog MAP kinase 14
    Protein for Dog MAP kinase 14

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    References
    1. 1.
      "p38 mitogen-activated protein kinase expression and activation in smooth muscle."
      Hedges J.C. , Yamboliev I.A. , Ngo M. , Horowitz B. , Adam L.P. , Gerthoffer W.T.
      Am. J. Physiol.275:C527-C534(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Smooth muscle.
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