Mob1a ELISA Kit for Rat(Rattus norvegicus) | EIAab.comMob1a ELISA Kit for Rat(Rattus norvegicus)

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Mob1a (Gene name),

MOB kinase activator 1A (Protein name ), MOB1A_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mob1a(Mobk1b;Mobkl1b);

Protein name:

MOB kinase activator 1A;

Alternative:

Mps one binder kinase activator-like 1B;Mob1 homolog 1B;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds STK38 and STK38L. Interacts with LATS1 and LATS2 (By similarity). Forms a tripartite complex with STK38 and STK3/MST2.

Function:

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

216

Sequence:

50:

100:

150:

200:

216:

LAPLQELIEK | LGSKDR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:297387

STRING:

10116.ENSRNOP00000063824

SMR:

Q3T1J9

Pfam:

PF03637

UniGene:

Rn.74475

Uniprot:

Q3T1J9

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ELISA Kit for Rat MOB kinase activator 1A

Cat.:

E2914r

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MSDS:

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Packing:

96T

ELISA Kit for Rat MOB kinase activator 1A

Cat.:

E2914h

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MSDS:

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Packing:

96T

ELISA Kit for Rat MOB kinase activator 1A

Cat.:

E2914m

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MSDS:

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Packing:

96T

CLIA Kit for Rat MOB kinase activator 1A

Cat.:

U2914h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat MOB kinase activator 1A

Cat.:

U2914m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat MOB kinase activator 1A

Cat.:

U2914r

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat MOB kinase activator 1A

Cat.:

P2914Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MOB kinase activator 1A

Cat.:

P2914Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MOB kinase activator 1A

Cat.:

P2914Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat MOB kinase activator 1A

Protein for Rat MOB kinase activator 1A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Prostate.

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