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Index > Protein center > Mtbp(Gene name) > Mouse
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  • Mtbp (Gene name),
  • Mdm2-binding protein (Protein name ),  MTBP_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Mtbp;
    Protein name:
    Mdm2-binding protein(mMTBP);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with MDM2.
    Function:
    May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    894
    Sequence:
    50:
    MDRYLLLVTW | REGKFRSVAG | GEIEPGTEAT | SLESTDKQPD | LTATNIYHLL | 
    100:
    KRSISDSIHP | DDSTFPACSV | GGTPHSRKWF | FAVQAICGFY | QFCSSDWQEI | 
    150:
    HFDAEKDKIE | DVLQANIEEC | QSAVECFEED | DSNSRESLPL | ADLYEESAEN | 
    200:
    LHQLSDKLPA | PGRAMIDIIL | LPSDKDPPKL | KECLPIVGAL | KHLKEWHSAK | 
    250:
    VIIAGSYCEI | NCQKIAEYLS | ASVVPLEEFR | NAIDPRELWR | GEIQMRERKF | 
    300:
    GFEISFPEFC | LKGVTPTNVS | AYNLNTCFLA | KKIASSKVFH | YYGPALEFVQ | 
    350:
    MIKLSDLPSC | YMSDIEFELE | VTGHCTRQNS | MLLLEQISSL | CGKVGALFVL | 
    400:
    PCTVSNVLIP | PPSQLASRKW | KEYMAKKPKT | ISVPDVAVKG | EFSGYHLLLQ | 
    450:
    GMGKRKCRAT | LLHSASQING | SFALSVIHGK | MKTKAGEARP | SFPFDFSSLP | 
    500:
    RFSEEQVLQR | EKQLASFQVL | ALKECLKRRK | AANQPEAFSA | DELKSLLALT | 
    550:
    RERFLGHFDV | LPTEAALAQT | DTVKAAGVVN | DDGTVEPYSS | SLMETNPLEW | 
    600:
    PERHVLQNLE | TSEKAKQKMR | TGSLPRSSEQ | LLGHKEGPRD | SLTLLDAKEL | 
    650:
    LKYFTSDGLP | VGDLQPLHIQ | RGEKPFVLTP | ELSPGKLQVL | PFEKASECHY | 
    700:
    HGIEYCLDDQ | KALERDGGFS | ELQSRLIRYE | TQTTCTRDSF | PVPTVLSPLP | 
    750:
    SPAVLSEPQS | VPEGEALQGE | LRTEVSGLKR | RSKDPSCLYP | QKRLTRSESS | 
    800:
    DCLPSQASCN | SNHHHHTGKP | RKPQAERCVS | GLPLPGREAS | KDTSKTSSGQ | 
    850:
    KRAHESKSSK | QMKESRSQKH | TRMLKEVVKD | TLKRHHITEA | HESFTACSQR | 
    894:
    LFDISKFYLK | DLKTSRGLFE | EMKKTANNNV | VQVIEWVVEK | MSKK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse mMTBP
    Cat.:
    E1159h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse mMTBP
    Cat.:
    E1159m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse mMTBP
    Cat.:
    U1159h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse mMTBP
    Cat.:
    U1159m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse mMTBP
    Cat.:
    P1159Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse mMTBP
    Cat.:
    P1159Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse mMTBP
    Monoclonal Antibody for Mouse mMTBP
    Protein for Mouse mMTBP
    Protein for Mouse mMTBP

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2."
      Boyd M.T. , Vlatkovic N. , Haines D.S.
      J. Biol. Chem.275:31883-31890(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH MDM2;TISSUE SPECIFICITY
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Aorta.
      tissue: Embryo.
      tissue: Thymus.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: FVB/N.
      tissue: Limb.
      tissue: Mammary tumor.
    4. 4.
      "Regulation of p53 and MDM2 activity by MTBP."
      Brady M. , Vlatkovic N. , Boyd M.T.
      Mol. Cell. Biol.25:545-553(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
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