Nr1h4 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comNr1h4 ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Nr1h4(Gene name) > Rat

Nr1h4 (Gene name),

Bile acid receptor (Protein name ), NR1H4_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Nr1h4(Bar;Fxr;Rip14);

Protein name:

Bile acid receptor;

Alternative:

Farnesol receptor HRR-1;Farnesoid X-activated receptor;Retinoid X receptor-interacting protein 14(RXR-interacting protein 14);Nuclear receptor subfamily 1 group H member 4;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with CARM1 and SMARD1. After activation by agonist binding, interacts with a coactivator, NCOA1 or NCOA2 (By similarity). Heterodimer of NR1H4 and RXR.

Function:

Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) and activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 within its gene locus.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

469

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

469:

WRVNDHKFTP | LLCEIWDVQ

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

Q62735

Pfam:

PF00104

UniGene:

Rn.42943

KEGG:

rno:60351

SMR:

Q62735

Uniprot:

Q62735

FOR

ELISA Kit for Rat Bile acid receptor

Cat.:

E2042h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat Bile acid receptor

Cat.:

E2042r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat Bile acid receptor

Cat.:

E2042m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Rat Bile acid receptor

Cat.:

E2042b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Bile acid receptor

Cat.:

U2042b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Bile acid receptor

Cat.:

U2042r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Bile acid receptor

Cat.:

U2042m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Bile acid receptor

Cat.:

U2042h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Rat Bile acid receptor

Cat.:

P2042Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Bile acid receptor

Cat.:

P2042Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Bile acid receptor

Cat.:

P2042Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Bile acid receptor

Protein for Rat Bile acid receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of a nuclear receptor that is activated by farnesol metabolites."
Forman B.M. , Goode E. , Chen J. , Oro A.E. , Bradley D.J. , Perlmann T. , Noonan D.J. , Burka L.T. , McMorris T. , Lamph W.W. , Evans R.M. , Weinberger C.
Cell81:687-693(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH RXR;INDUCTION
strain: Lewis.
tissue: Liver.
2.

"Structural basis for bile acid binding and activation of the nuclear receptor FXR."
Mi L.Z. , Devarakonda S. , Harp J.M. , Han Q. , Pellicciari R. , Willson T.M. , Khorasanizadeh S. , Rastinejad F.
Mol. Cell11:1093-1100(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 241-469 IN COMPLEXES WITH CHENODEOXYCHOLIC ACID ANALOGS AND NCOA2 COACTIVATOR PEPTIDE

Product Feedback Wall

* Email:
*Comments: