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Index > Protein center > PEAK1(Gene name) > Human
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  • PEAK1 (Gene name),
  • Pseudopodium-enriched atypical kinase 1 (Protein name ),  PEAK1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PEAK1(KIAA2002);
    Protein name:
    Pseudopodium-enriched atypical kinase 1;
    Alternative:
    Tyrosine-protein kinase SgK269;Sugen kinase 269;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with BCAR1 and CRK.
    Function:
    Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN.
    Subcellular Location:
    Cytoplasm cytoskeleton Cell junction focal adhesion Colocalizes with F-actin in serum-rich medium. Actin colocalization is reduced during serum starvation.
    Protein Attributes:
    Sequence length:
    1746
    Sequence:
    50:
    MSACNTFTEH | VWKPGECKNC | FKPKSLHQLP | PDPEKAPITH | GNVKTNANHS | 
    100:
    NNHRIRNTGN | FRPPVAKKPT | IAVKPTMIVA | DGQSICGELS | IQEHCENKPV | 
    150:
    IIGWNRNRAA | LSQKPLNNNN | EDDEGISHVP | KPYGNNDSAK | KMSDNNNGLT | 
    200:
    EVLKEIAGLD | TAPQIRGNET | NSRETFLGRI | NDCYKRSLER | KLPPSCMIGG | 
    250:
    IKETQGKHVI | LSGSTEVISN | EGGRFCYPEF | SSGEESEEDV | LFSNMEEEHE | 
    300:
    SWDESDEELL | AMEIRMRGQP | RFANFRANTL | SPVRFFVDKK | WNTIPLRNKS | 
    350:
    LQRICAVDYD | DSYDEILNGY | EENSVVSYGQ | GSIQSMVSSD | STSPDSSLTE | 
    400:
    ESRSETASSL | SQKICNGGLS | PGNPGDSKDM | KEIEPNYESP | SSNNQDKDSS | 
    450:
    QASKSSIKVP | ETHKAVLALR | LEEKDGKIAV | QTEKEESKAS | TDVAGQAVTI | 
    500:
    NLVPTEEQAK | PYRVVNLEQP | LCKPYTVVDV | SAAMASEHLE | GPVNSPKTKS | 
    550:
    SSSTPNSPVT | SSSLTPGQIS | AHFQKSSAIR | YQEVWTSSTS | PRQKIPKVEL | 
    600:
    ITSGTGPNVP | PRKNCHKSAP | TSPTATNISS | KTIPVKSPNL | SEIKFNSYNN | 
    650:
    AGMPPFPIII | HDEPTYARSS | KNAIKVPIVI | NPNAYDNLAI | YKSFLGTSGE | 
    700:
    LSVKEKTTSV | ISHTYEEIET | ESKVPDNTTS | KTTDCLQTKG | FSNSTEHKRG | 
    750:
    SVAQKVQEFN | NCLNRGQSSP | QRSYSSSHSS | PAKIQRATQE | PVAKIEGTQE | 
    800:
    SQMVGSSSTR | EKASTVLSQI | VASIQPPQSP | PETPQSGPKA | CSVEELYAIP | 
    850:
    PDADVAKSTP | KSTPVRPKSL | FTSQPSGEAE | APQTTDSPTT | KVQKDPSIKP | 
    900:
    VTPSPSKLVT | SPQSEPPAPF | PPPRSTSSPY | HAGNLLQRHF | TNWTKPTSPT | 
    950:
    RSTEAESVLH | SEGSRRAADA | KPKRWISFKS | FFRRRKTDEE | DDKEKEREKG | 
    1000:
    KLVGLDGTVI | HMLPPPPVQR | HHWFTEAKGE | SSEKPAIVFM | YRCDPAQGQL | 
    1050:
    SVDQSKARTD | QAAVMEKGRA | ENALLQDSEK | KRSHSSPSQI | PKKILSHMTH | 
    1100:
    EVTEDFSPRD | PRTVVGKQDG | RGCTSVTTAL | SLPELEREDG | KEDISDPMDP | 
    1150:
    NPCSATYSNL | GQSRAAMIPP | KQPRQPKGAV | DDAIAFGGKT | DQEAPNASQP | 
    1200:
    TPPPLPKKMI | IRANTEPISK | DLQKSMESSL | CVMANPTYDI | DPNWDASSAG | 
    1250:
    SSISYELKGL | DIESYDSLER | PLRKERPVPS | AANSISSLTT | LSIKDRFSNS | 
    1300:
    MESLSSRRGP | SCRQGRGIQK | PQRQALYRGL | ENREEVVGKI | RSLHTDALKK | 
    1350:
    LAVKCEDLFM | AGQKDQLRFG | VDSWSDFRLT | SDKPCCEAGD | AVYYTASYAK | 
    1400:
    DPLNNYAVKI | CKSKAKESQQ | YYHSLAVRQS | LAVHFNIQQD | CGHFLAEVPN | 
    1450:
    RLLPWEDPDD | PEKDEDDMEE | TEEDAKGETD | GKNPKPCSEA | ASSQKENQGV | 
    1500:
    MSKKQRSHVV | VITREVPCLT | VADFVRDSLA | QHGKSPDLYE | RQVCLLLLQL | 
    1550:
    CSGLEHLKPY | HVTHCDLRLE | NLLLVHYQPG | GTAQGFGPAE | PSPTSSYPTR | 
    1600:
    LIVSNFSQAK | QKSHLVDPEI | LRDQSRLAPE | IITATQYKKC | DEFQTGILIY | 
    1650:
    EMLHLPNPFD | ENPELKEREY | TRADLPRIPF | RSPYSRGLQQ | LASCLLNPNP | 
    1700:
    SERILISDAK | GILQCLLWGP | REDLFQTFTA | CPSLVQRNTL | LQNWLDIKRT | 
    1746:
    LLMIKFAEKS | LDREGGISLE | DWLCAQYLAF | ATTDSLSCIV | KILQHR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    MIM:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Pseudopodium-enriched atypical kinase 1
    Cat.:
    E15408h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Pseudopodium-enriched atypical kinase 1
    Cat.:
    E15408m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Pseudopodium-enriched atypical kinase 1
    Cat.:
    U15408h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Pseudopodium-enriched atypical kinase 1
    Cat.:
    U15408m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Pseudopodium-enriched atypical kinase 1
    Cat.:
    P15408Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Pseudopodium-enriched atypical kinase 1
    Cat.:
    P15408Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Pseudopodium-enriched atypical kinase 1
    Monoclonal Antibody for Human Pseudopodium-enriched atypical kinase 1
    Protein for Human Pseudopodium-enriched atypical kinase 1
    Protein for Human Pseudopodium-enriched atypical kinase 1

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 537-1746
      tissue: Lung.
      tissue: Mesangial cell.
      tissue: Smooth muscle.
    2. 3.
      "The nucleotide sequence of a long cDNA clone isolated from human spleen."
      Jikuya H. , Takano J. , Nomura N. , Kikuno R. , Nagase T. , Ohara O.
      Submitted (2002-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 707-1120
      tissue: Spleen.
    3. 4.
      "Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method."
      Ohara O. , Nagase T. , Mitsui G. , Kohga H. , Kikuno R. , Hiraoka S. , Takahashi Y. , Kitajima S. , Saga Y. , Koseki H.
      DNA Res.9:47-57(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 983-1746
      tissue: Brain.
    4. 5.
      "The protein kinase complement of the human genome."
      Manning G. , Whyte D.B. , Martinez R. , Hunter T. , Sudarsanam S.
      Science298:1912-1934(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
    5. 6.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    6. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-540 AND SER-587;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 8.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;INTERACTION WITH BCAR1 AND CRK;SUBCELLULAR LOCATION;AUTOPHOSPHORYLATION;PHOSPHORYLATION BY CSK
    9. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    10. 11.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-281 AND TYR-635;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 12.
      "Patterns of somatic mutation in human cancer genomes."
      Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
      Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] ARG-213; ILE-240; PRO-440; GLN-611; ILE-792; GLU-836; PHE-1035; LYS-1071; PRO-1077; LEU-1145; GLN-1408; THR-1542 AND GLY-1699
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