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Index > Protein center > PPIF(Gene name) > Human
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  • PPIF (Gene name),
  • Peptidyl-prolyl cis-trans isomerase F, mitochondrial (Protein name ),  PPIF_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PPIF(CYP3);
    Protein name:
    Peptidyl-prolyl cis-trans isomerase F, mitochondrial(PPIase F);
    Alternative:
    Rotamase F;Cyclophilin F(CyP-D);Rotamase F;Mitochondrial cyclophilin(CyP-M);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
    Subcellular Location:
    Mitochondrion matrix
    Protein Attributes:
    Sequence length:
    207
    Sequence:
    50:
    MLALRCGSRW | LGLLSVPRSV | PLRLPAARAC | SKGSGDPSSS | SSSGNPLVYL | 
    100:
    DVDANGKPLG | RVVLELKADV | VPKTAENFRA | LCTGEKGFGY | KGSTFHRVIP | 
    150:
    SFMCQAGDFT | NHNGTGGKSI | YGSRFPDENF | TLKHVGPGVL | SMANAGPNTN | 
    200:
    GSQFFICTIK | TDWLDGKHVV | FGHVKEGMDV | VKKIESFGSK | SGRTSKKIVI | 
    207:
    TDCGQLS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human PPIase F
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human PPIase F
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    ELISA Kit for Human PPIase F
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    ELISA Kit for Human PPIase F
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human PPIase F
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human PPIase F
    Cat.:
    U9275h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human PPIase F
    Cat.:
    U9275b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human PPIase F
    Cat.:
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    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human PPIase F
    Cat.:
    P9275Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PPIase F
    Cat.:
    P9275Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PPIase F
    Polyclonal Antibody for Human PPIase F
    Cat.:
    P9275Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human PPIase F
    Monoclonal Antibody for Human PPIase F
    Monoclonal Antibody for Human PPIase F
    Monoclonal Antibody for Human PPIase F
    Protein for Human PPIase F
    Protein for Human PPIase F
    Protein for Human PPIase F
    Protein for Human PPIase F

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    References
    1. 1.
      "The cyclophilin multigene family of peptidyl-prolyl isomerases. Characterization of three separate human isoforms."
      Bergsma D.J. , Eder C. , Gross M. , Kersten H. , Sylvester D. , Appelbaum E. , Cusimano D. , Livi G.P. , McLauglin M.M. , Kasyan K. , Porter T.G. , Silverman C. , Dunnington D. , Hand A. , Prichett W.P. , Bossard M.J. , Brandt M. , Levy M.A.
      J. Biol. Chem.266:23204-23214(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Umbilical cord blood.
    3. 3.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Blood.
      tissue: Ovary.
    6. 6.
      "Import and processing of heart mitochondrial cyclophilin D."
      Johnson N. , Khan A. , Virji S. , Ward J.M. , Crompton M.
      Eur. J. Biochem.263:353-359(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    7. 7.
      "Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect."
      Eliseev R.A. , Malecki J. , Lester T. , Zhang Y. , Humphrey J. , Gunter T.E.
      J. Biol. Chem.284:9692-9699(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH BCL2
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Complement 1q-binding protein inhibits the mitochondrial permeability transition pore and protects against oxidative stress-induced death."
      McGee A.M. , Baines C.P.
      Biochem. J.433:119-125(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH C1QBP
    10. 10.
      "Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore."
      Nguyen T.T. , Stevens M.V. , Kohr M. , Steenbergen C. , Sack M.N. , Murphy E.
      J. Biol. Chem.286:40184-40192(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF CYS-203
    11. 11.
      "p53 opens the mitochondrial permeability transition pore to trigger necrosis."
      Vaseva A.V. , Marchenko N.D. , Ji K. , Tsirka S.E. , Holzmann S. , Moll U.M.
      Cell149:1536-1548(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TP53
    12. 12.
      "Crystal engineering yields crystals of cyclophilin D diffracting to 1.7 A resolution."
      Schlatter D. , Thoma R. , Kung E. , Stihle M. , Muller F. , Borroni E. , Cesura A. , Hennig M.
      Acta Crystallogr. D61:513-519(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.71 ANGSTROMS) OF 43-207
    13. 13.
      "Crystal structure of human cyclophilin D in complex with its inhibitor, cyclosporin A at 0.96-A resolution."
      Kajitani K. , Fujihashi M. , Kobayashi Y. , Shimizu S. , Tsujimoto Y. , Miki K.
      Proteins70:1635-1639(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (0.96 ANGSTROMS) OF 44-207 IN COMPLEX WITH CYCLOSPORIN A
    14. 14.
      "In-plate protein crystallization, in situ ligand soaking and X-ray diffraction."
      le Maire A. , Gelin M. , Pochet S. , Hoh F. , Pirocchi M. , Guichou J.F. , Ferrer J.L. , Labesse G.
      Acta Crystallogr. D67:747-755(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.54 ANGSTROMS) OF 44-207
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