PYGM ELISA Kit for Human(Homo sapiens) | EIAab.comPYGM ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PYGM(Gene name) > Human

PYGM (Gene name),

Glycogen phosphorylase, muscle form (Protein name ), PYGM_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PYGM;

Protein name:

Glycogen phosphorylase, muscle form;

Alternative:

Myophosphorylase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer. Dimers associate into a tetramer to form the enzymatically active phosphorylase A.

Function:

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

842

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

842:

MVIRNIATSG | KFSSDRTIAQ | YAREIWGVEP | SRQRLPAPDE | AI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P11217

KEGG:

hsa:5837

STRING:

9606.ENSP00000164139

MIM:

232600

String:

P11217

Pfam:

PF00343

UniGene:

Hs.154084

Uniprot:

P11217

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ELISA Kit for Human Glycogen phosphorylase, muscle form

Cat.:

E0848h

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96T

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ELISA Kit for Human Glycogen phosphorylase, muscle form

Cat.:

E0848r

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Looking for manual.

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96T

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ELISA Kit for Human Glycogen phosphorylase, muscle form

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ELISA Kit for Human Glycogen phosphorylase, muscle form

Cat.:

E0848b

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Packing:

96T

ELISA Kit for Human Glycogen phosphorylase, muscle form

Cat.:

E0848m

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96T

CLIA Kit for Human Glycogen phosphorylase, muscle form

MSDS:

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CLIA Kit for Human Glycogen phosphorylase, muscle form

Cat.:

U0848h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Glycogen phosphorylase, muscle form

Cat.:

U0848r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Glycogen phosphorylase, muscle form

Cat.:

U0848b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Glycogen phosphorylase, muscle form

Cat.:

U0848m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Glycogen phosphorylase, muscle form

Cat.:

P0848Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Glycogen phosphorylase, muscle form

Cat.:

P0848Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Glycogen phosphorylase, muscle form

Cat.:

P0848Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Glycogen phosphorylase, muscle form

Protein for Human Glycogen phosphorylase, muscle form

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Intron/exon structure of the human gene for the muscle isozyme of glycogen phosphorylase."
Burke J. , Hwang P.K. , Anderson L. , Lebo R. , Gorin F. , Fletterick R.J.
Proteins2:177-187(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Molecular diagnosis of McArdle disease: revised genomic structure of the myophosphorylase gene and identification of a novel mutation."
Kubisch C. , Wicklein E.M. , Jentsch T.J.
Hum. Mutat.12:27-32(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

Carty M.D. , Clancy Y.C. , Soeller W.C.
Submitted (1998-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Muscle.
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Tongue.
5.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
8.

"Comparative sequence analysis of rat, rabbit, and human muscle glycogen phosphorylase cDNAs."
Hwang P.K. , See Y.P. , Vincentini A.M. , Powers M.A. , Fletterick R.J. , Crerar M.M.
Eur. J. Biochem.152:267-274(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 676-842 (ISOFORM 1)
9.

"Molecular mechanisms of McArdle's disease (muscle glycogen phosphorylase deficiency). RNA and DNA analysis."
Gautron S. , Daegelen D. , Mennecier F. , Dubocq D. , Kahn A. , Dreyfus J.-C.
J. Clin. Invest.79:275-281(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 455-676 (ISOFORM 1)
10.

"Regulation of glycogen phosphorylase. Role of the peptide region surrounding the phosphoserine residue in determining enzyme properties."
Carty T.J. , Tu J. , Graves D.J.
J. Biol. Chem.250:4980-4985(1975) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-15
11.

"Molecular genetic heterogeneity of myophosphorylase deficiency (McArdle's disease)."
Tsujino S. , Shanske S. , Dimauro S.
N. Engl. J. Med.329:241-245(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GSD5 SER-205 AND THR-543
12.

"Two novel missense mutations (E654K, L396P) in Caucasian patients with myophosphorylase deficiency (McArdle's disease)."
Tsujino S. , Shanske S. , Martinuzzi A. , Heiman-Patterson T. , Dimauro S.
Hum. Mutat.6:276-277(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GSD5 PRO-397 AND LYS-655
13.

"The molecular genetic basis of myophosphorylase deficiency (McArdle's disease)."
Tsujino S. , Shanske S. , Nonaka I. , DiMauro S.
Muscle Nerve3:S23-S27(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GSD5 SER-205; PRO-292; PRO-397; THR-543; LYS-655 AND PHE-709 DEL
14.

"Mutation analysis in myophosphorylase deficiency (McArdle's disease)."
Vorgerd M. , Kubisch C. , Burwinkel B. , Reichmann H. , Mortier W. , Tettenborn B. , Pongratz D. , Lindemuth R. , Tegenthoff M. , Malin J.P. , Kilimann M.W.
Ann. Neurol.43:326-331(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GSD5 GLU-666 AND ARG-686
15.

"A new mutation in the regulatory domain of the myophosphorylase gene affecting protein dimer contact."
Gamez J. , Fernandez R. , Bruno C. , Andreu A.L. , Cervera C. , Navarro C. , Schwartz S. , Dimauro S.
Muscle Nerve22:1136-1138(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD5 PRO-116
16.

"A new mutation in the myophosphorylase gene (Asn684Tyr) in a Spanish patient with McArdle's disease."
Andreu A.L. , Bruno C. , Tamburino L. , Gamez J. , Shanske S. , Cervera C. , Navarro C. , DiMauro S.
Neuromuscul. Disord.9:171-173(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GSD5 SER-205 AND TYR-685
17.

"McArdle's disease associated with homozygosity for the missense mutation Gly204Ser of the myophosphorylase gene in a Spanish patient."
Rubio J.C. , Martin M.A. , Garcia A. , Campos Y. , Cabello A. , Culebras J.M. , Arenas J.
Neuromuscul. Disord.9:174-175(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD5 SER-205
18.

"A novel missense mutation (W797R) in the myophosphorylase gene in Spanish patients with McArdle disease."
Fernandez R. , Navarro C. , Andreu A.L. , Bruno C. , Shanske S. , Gamez J. , Teijeira S. , Hernandez I. , Teijeiro A. , Fernandez J.M. , Musumeci O. , DiMauro S.
Arch. Neurol.57:217-219(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD5 ARG-798
19.

"A missense mutation W797R in the myophosphorylase gene in a Spanish patient with McArdle's disease."
Rubio J.C. , Martin M.A. , Campos Y. , Auciello R. , Cabello A. , Arenas J.
Muscle Nerve23:129-131(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD5 ARG-798
20.

"A missense mutation T487N in the myophosphorylase gene in a Spanish patient with McArdle's disease."
Rubio J.C. , Martin M.A. , Campos Y. , Cabello A. , Arenas J.
Neuromuscul. Disord.10:138-140(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD5 ASN-488
21.

"A homozygous missense mutation (A659D) in the myophosphorylase gene in a Spanish patient with McArdle's disease."
Martin M.A. , Rubio J.C. , Campos Y. , Ricoy J.R. , Cabello A. , Arenas J.
Neuromuscul. Disord.10:447-449(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD5 ASP-660
22.

"Molecular heterogeneity of myophosphorylase deficiency (McArdle's disease): a genotype-phenotype correlation study."
Martin M.A. , Rubio J.C. , Buchbinder J. , Fernandez-Hojas R. , del Hoyo P. , Teijeira S. , Gamez J. , Navarro C. , Fernandez J.M. , Cabello A. , Campos Y. , Cervera C. , Culebras J.M. , Andreu A.L. , Fletterick R.J. , Arenas J.
Ann. Neurol.50:574-581(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GSD5 PRO-116; TRP-194; SER-205; LYS-349; ASN-488; TRP-602; ASP-660; TYR-685; VAL-704 AND ARG-798
23.

"Two new mutations in the myophosphorylase gene in Italian patients with McArdle's disease."
Bruno C. , Lanzillo R. , Biedi C. , Iadicicco L. , Minetti C. , Santoro L.
Neuromuscul. Disord.12:498-500(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD5 PRO-687

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