SETD8 ELISA Kit for Bovine(Bos taurus) | EIAab.comSETD8 ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > SETD8(Gene name) > Bovine

SETD8 (Gene name),

N-lysine methyltransferase SETD8 (Protein name ), SETD8_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

SETD8;

Protein name:

N-lysine methyltransferase SETD8;

Alternative:

2.1.1.43;Histone-lysine N-methyltransferase SETD8);H4-K20-HMTase SETD8;SET domain-containing protein 8;PR/SET domain-containing protein 07(PR-Set7;PR/SET07);

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Interacts with L3MBTL1.

Function:

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes.

Subcellular Location:

Nucleus Chromosome Specifically localizes to mitotic chromosomes. Associates with silent chromatin on euchromatic arms. Not associated with constitutive heterochromatin.

Protein Attributes:

Sequence length:

352

Sequence:

50:

100:

150:

200:

250:

300:

350:

352:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00856

SMR:

Q2YDJ8

UniGene:

Bt.65045

STRING:

9913.ENSBTAP00000000160

String:

Q2YDJ8

KEGG:

bta:532622

Uniprot:

Q2YDJ8

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ELISA Kit for Bovine N-lysine methyltransferase SETD8

Cat.:

E3859b

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Bovine N-lysine methyltransferase SETD8

Cat.:

E3859m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Bovine N-lysine methyltransferase SETD8

Cat.:

E3859h

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Packing:

96T

CLIA Kit for Bovine N-lysine methyltransferase SETD8

Cat.:

U3859m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine N-lysine methyltransferase SETD8

Cat.:

U3859b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine N-lysine methyltransferase SETD8

Cat.:

U3859h

Price:

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Packing:

96T

Polyclonal Antibody for Bovine N-lysine methyltransferase SETD8

Cat.:

P3859Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine N-lysine methyltransferase SETD8

Cat.:

P3859Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine N-lysine methyltransferase SETD8

Monoclonal Antibody for Bovine N-lysine methyltransferase SETD8

Protein for Bovine N-lysine methyltransferase SETD8

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2005-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Crossbred X Angus.
tissue: Liver.

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