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Index > Protein center > SLAMF1(Gene name) > Dog
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  • SLAMF1 (Gene name),
  • Signaling lymphocytic activation molecule (Protein name ),  SLAF1_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SLAMF1(SLAM);
    Protein name:
    Signaling lymphocytic activation molecule;
    Alternative:

    CD:
    CD150;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Interacts (via cytoplasmic domain) with SH2D1A, and with PTPN11. Interacts with INPP5D/SHIP1 (By similarity). Interacts with canine distemper virus HN protein; suggesting that it may serve as a receptor.
    Function:
    High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein Present on the surface of B-cells and T-cells.
    Protein Attributes:
    Sequence length:
    342
    Sequence:
    50:
    MDSRGFLSLR | CLLVLALASK | LSCGTGESLM | NCPEVPGKLG | SSLQLSLASE | 
    100:
    GISKRMNKSI | HILVTRAESP | GNSIKKKIVS | LDLPEGGSPR | YLENGYKFHL | 
    150:
    ENLTLRILES | RRENEGWYFM | TLEENFSVQH | FCLQLKLYEQ | VSTPEIKVLN | 
    200:
    WTQENGNCSM | MLACEVEKGD | NVVYSWSEKL | GIDPLIPANS | SHLLHLSLGP | 
    250:
    QHVNNVYVCT | VSNPVSNRSW | SFNPWSKCRP | ESSVPRQWRL | YAGLFLGGIV | 
    300:
    GVILIFEVVL | LLLRRRGKTN | HYKPTKEEKS | LTIYAQVQKS | GSTQKKPDPL | 
    342:
    PAEDPCTTIY | VAATEPVPEP | APEPVQEPHS | ITVYASVTFP | ES
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Dog Signaling lymphocytic activation molecule
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    Packing:
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    ELISA Kit for Dog Signaling lymphocytic activation molecule
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    E9273h
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    ELISA Kit for Dog Signaling lymphocytic activation molecule
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    E9273m
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    Packing:
    96T
    CLIA Kit for Dog Signaling lymphocytic activation molecule
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    U9273d
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    Packing:
    96T
    CLIA Kit for Dog Signaling lymphocytic activation molecule
    Cat.:
    U9273h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog Signaling lymphocytic activation molecule
    Cat.:
    U9273m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Dog Signaling lymphocytic activation molecule
    Cat.:
    P9273Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Signaling lymphocytic activation molecule
    Cat.:
    P9273Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Signaling lymphocytic activation molecule
    Monoclonal Antibody for Dog Signaling lymphocytic activation molecule
    Monoclonal Antibody for Dog Signaling lymphocytic activation molecule
    Monoclonal Antibody for Dog Signaling lymphocytic activation molecule
    Protein for Dog Signaling lymphocytic activation molecule
    Protein for Dog Signaling lymphocytic activation molecule
    Protein for Dog Signaling lymphocytic activation molecule

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    References
    1. 1.
      "Morbilliviruses use signaling lymphocyte activation molecules (CD150) as cellular receptors."
      Tatsuo H. , Ono N. , Yanagi Y.
      J. Virol.75:5842-5850(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH CANINE DISTEMPER VIRUS HN PROTEIN
    2. 2.
      "CD150 is a cellular receptor for canine distemper virus."
      Richardson C.D.
      Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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