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Index > Protein center > TNFSF13B(Gene name) > Human
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  • TNFSF13B (Gene name),
  • Tumor necrosis factor ligand superfamily member 13B (Protein name ),  TN13B_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TNFSF13B(UNQ401/PRO738;BAFF;BLYS;TALL1;TNFSF20;ZTNF4);
    Protein name:
    Tumor necrosis factor ligand superfamily member 13B;
    Alternative:
    B-cell-activating factor;B lymphocyte stimulator(BLyS);Dendritic cell-derived TNF-like molecule;BAFF;TNF- and APOL-related leukocyte expressed ligand 1(TALL-1);
    CD:
    CD257;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotrimer. Isoform 2 heteromultimerizes with isoform 1, probably limiting the amount of functional isoform 1 on the cell surface.
    Function:
    Isoform 2 seems to inhibit isoform 1 secretion and bioactivity.
    Subcellular Location:
    Tumor necrosis factor ligand superfamily member 13b, soluble form Secreted
    Protein Attributes:
    Sequence length:
    285
    Sequence:
    50:
    MDDSTEREQS | RLTSCLKKRE | EMKLKECVSI | LPRKESPSVR | SSKDGKLLAA | 
    100:
    TLLLALLSCC | LTVVSFYQVA | ALQGDLASLR | AELQGHHAEK | LPAGAGAPKA | 
    150:
    GLEEAPAVTA | GLKIFEPPAP | GEGNSSQNSR | NKRAVQGPEE | TVTQDCLQLI | 
    200:
    ADSETPTIQK | GSYTFVPWLL | SFKRGSALEE | KENKILVKET | GYFFIYGQVL | 
    250:
    YTDKTYAMGH | LIQRKKVHVF | GDELSLVTLF | RCIQNMPETL | PNNSCYSAGI | 
    285:
    AKLEEGDELQ | LAIPRENAQI | SLDGDVTFFG | ALKLL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    MIM:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tumor necrosis factor ligand superfamily member 13B
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    E1686h
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    96T
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    ELISA Kit for Human Tumor necrosis factor ligand superfamily member 13B
    Cat.:
    E1686m
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    MSDS:
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    96T
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    CLIA Kit for Human Tumor necrosis factor ligand superfamily member 13B
    Cat.:
    U1686m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Tumor necrosis factor ligand superfamily member 13B
    Cat.:
    U1686h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 13B
    Cat.:
    P1686Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 13B
    Cat.:
    P1686Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 13B
    Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 13B
    Protein for Human Tumor necrosis factor ligand superfamily member 13B
    Protein for Human Tumor necrosis factor ligand superfamily member 13B

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "TALL-1 is a novel member of the TNF family that is down-regulated by mitogens."
      Shu H.-B. , Hu W.-H. , Johnson H.
      J. Leukoc. Biol.65:680-683(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 134-148
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Monocyte.
      tissue: Neutrophil.
    4. 4.
      "DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF."
      Gavin A.L. , Ait-Azzouzene D. , Ware C.F. , Nemazee D.
      J. Biol. Chem.278:38220-38228(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY;SUBUNIT
    5. 5.
      "The complexity of the BAFF TNF-family members: implications for autoimmunity."
      Lahiri A. , Pochard P. , Le Pottier L. , Tobon G.J. , Bendaoud B. , Youinou P. , Pers J.O.
      J. Autoimmun.39:189-198(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);FUNCTION (ISOFORM 3);SUBUNIT;ALTERNATIVE SPLICING
    6. 6.
      "Homo sapiens homolog of tumor necrosis factor."
      Farrah T. , Gross J. , Piddington C. , O'Hara P.
      Submitted (1999-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    7. 7.
      "A novel dendritic cell-derived TNF-like molecule."
      Zhang W. , Wan T. , Yu Y. , Cao X.
      Submitted (1999-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Dendritic cell.
    8. 8.
      Gao H. , He F. , Li R.
      Submitted (2002-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    10. 10.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    11. 11.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    12. 12.
      "The DNA sequence and analysis of human chromosome 13."
      Dunham A. , Matthews L.H. , Burton J. , Ashurst J.L. , Howe K.L. , Ashcroft K.J. , Beare D.M. , Burford D.C. , Hunt S.E. , Griffiths-Jones S. , Jones M.C. , Keenan S.J. , Oliver K. , Scott C.E. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews D.T. , more...
      Nature428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    14. 14.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    15. 15.
      "New polymorphisms of human BLyS gene."
      Kawasaki A. , Tsuchiya N. , Fukazawa T. , Hashimoto H. , Tokunaga K.
      Submitted (2001-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-135;VARIANT THR-105
    16. 16.
      "APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity."
      Yu G. , Boone T. , Delaney J. , Hawkins N. , Kelley M.J. , Ramakrishnan M. , McCabe S. , Qiu W.R. , Kornuc M. , Xia X.-Z. , Guo J. , Stolina M. , Boyle W.J. , Sarosi I. , Hsu H. , Senaldi G. , Theill L.E.
      Nat. Immunol.1:252-256(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    17. 17.
      "Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands."
      Liu Y. , Xu L. , Opalka N. , Kappler J. , Shu H.-B. , Zhang G.
      Cell108:383-394(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 142-285
    18. 18.
      "Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes."
      Karpusas M. , Cachero T.G. , Qian F. , Boriack-Sjodin A. , Mullen C. , Strauch K. , Hsu Y.-M. , Kalled S.L.
      J. Mol. Biol.315:1145-1154(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 136-285
    19. 19.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 134-285
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