TYRP1 ELISA Kit for Human(Homo sapiens) | EIAab.comTYRP1 ELISA Kit for Human(Homo sapiens)

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TYRP1 (Gene name),

5,6-dihydroxyindole-2-carboxylic acid oxidase (Protein name ), TYRP1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TYRP1(CAS2;TYRP;TYRRP);

Protein name:

5,6-dihydroxyindole-2-carboxylic acid oxidase(DHICA oxidase);

Alternative:

Glycoprotein 75;Catalase B;Tyrosinase-related protein 1(TRP;TRP-1;TRP1);Melanoma antigen gp75;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.

Subcellular Location:

Melanosome membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

537

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

537:

IRARRSMDEA | NQPLLTDQYQ | CYAEEYEKLQ | NPNQSVV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000373570

SMR:

P17643

UniGene:

Hs.270279

KEGG:

hsa:7306

Pfam:

PF00264

MIM:

115501

String:

P17643

Uniprot:

P17643

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ELISA Kit for Human DHICA oxidase

Cat.:

E9854m

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Packing:

96T

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ELISA Kit for Human DHICA oxidase

Cat.:

E9854h

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96T

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ELISA Kit for Human DHICA oxidase

Cat.:

E9854b

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Packing:

96T

ELISA Kit for Human DHICA oxidase

Cat.:

E9854c

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96T

CLIA Kit for Human DHICA oxidase

Cat.:

U9854c

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Packing:

96T

CLIA Kit for Human DHICA oxidase

Cat.:

U9854h

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Packing:

96T

CLIA Kit for Human DHICA oxidase

Cat.:

U9854m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human DHICA oxidase

Cat.:

U9854b

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Packing:

96T

Polyclonal Antibody for Human DHICA oxidase

Cat.:

P9854Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human DHICA oxidase

Cat.:

P9854Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human DHICA oxidase

Protein for Human DHICA oxidase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Nucleotide sequence of the cDNA encoding human tyrosinase-related protein."
Cohen T. , Muller R.M. , Tomita Y. , Shibahara S.
Nucleic Acids Res.18:2807-2807(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Melanoma.
2.

"Mapping the human CAS2 gene, the homologue of the mouse brown (b) locus, to human chromosome 9p22-pter."
Chintamaneni C.D. , Ramsay M. , Colman M.-A. , Fox M.F. , Pickard R.T. , Kwon B.S.
Biochem. Biophys. Res. Commun.178:227-235(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Complete sequence and polymorphism study of the human TYRP1 gene encoding tyrosinase-related protein 1."
Box N.F. , Wyeth J.R. , Mayne C.J. , O'Gorman L.E. , Martin N.G. , Sturm R.A.
Mamm. Genome9:50-53(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Skin.
5.

"Chromosomal structure of the human TYRP1 and TYRP2 loci and comparison of the tyrosinase-related protein gene family."
Sturm R.A. , O'Sullivan B.J. , Box N.F. , Smith A.G. , Smit S.E. , Puttick E.R.J. , Parsons P.G. , Dunn I.S.
Genomics29:24-34(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-128
tissue: Liver.
6.

"Downstream region of the human tyrosinase-related protein gene enhances its promoter activity."
Shibata K. , Takeda K. , Tomita Y. , Tagami H. , Shibahara S.
Biochem. Biophys. Res. Commun.184:568-575(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-17
7.

"The melanoma antigen gp75 is the human homologue of the mouse b (brown) locus gene product."
Vijayasaradhi S. , Bouchard B. , Houghton A.N.
J. Exp. Med.171:1375-1380(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 218-465;PARTIAL PROTEIN SEQUENCE
tissue: Melanoma.
8.

"Human tyrosinase-like protein (TYRL) carboxy terminus: closer homology with the mouse protein than previously reported."
Urquhart A.J.
Nucleic Acids Res.19:5803-5803(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 481-537
tissue: Blood.
tissue: Hair root.
9.

"Murine and human b locus pigmentation genes encode a glycoprotein (gp75) with catalase activity."
Halaban R. , Moellmann G.
Proc. Natl. Acad. Sci. U.S.A.87:4809-4813(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE FUNCTION
10.

"Proteomic analysis of early melanosomes: identification of novel melanosomal proteins."
Basrur V. , Yang F. , Kushimoto T. , Higashimoto Y. , Yasumoto K. , Valencia J. , Muller J. , Vieira W.D. , Watabe H. , Shabanowitz J. , Hearing V.J. , Hunt D.F. , Appella E.
J. Proteome Res.2:69-79(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue: Melanoma.
11.

"Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."
Chi A. , Valencia J.C. , Hu Z.-Z. , Watabe H. , Yamaguchi H. , Mangini N.J. , Huang H. , Canfield V.A. , Cheng K.C. , Yang F. , Abe R. , Yamagishi S. , Shabanowitz J. , Hearing V.J. , Wu C. , Appella E. , Hunt D.F.
J. Proteome Res.5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue: Melanoma.
12.

"Melanesian blond hair is caused by an amino acid change in TYRP1."
Kenny E.E. , Timpson N.J. , Sikora M. , Yee M.C. , Moreno-Estrada A. , Eng C. , Huntsman S. , Burchard E.G. , Stoneking M. , Bustamante C.D. , Myles S.
Science336:554-554(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SHEP11;VARIANT CYS-93;ASSOCIATION OF VARIANT CYS-93 WITH BLOND HAIR
13.

"Oculocutaneous albinism with TYRP1 gene mutations in a Caucasian patient."
Rooryck C. , Roudaut C. , Robine E. , Muesebeck J. , Arveiler B.
Pigment Cell Res.19:239-242(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT OCA3 GLN-356

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