Protein name:
Urocortin ;
Alternative:
Corticotensin ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with CRHR1 and CRHR2 (via their N-terminal extracellular domain).
Function:
Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta.
Subcellular Location:
Secreted
Protein Attributes:
50:
MRQRGRATLL | VALLLLVQLR | PESSQWSPAA | AAANVVQDPN | LRWNPGVRNQ |
100:
GGGVRALLLL | LAERFPRRAG | SEPAGERQRR | DDPPLSIDLT | FHLLRTLLEL |
122:
ARTQSQRERA | EQNRIIFDSV | GK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Rat Urocortin
ELISA Kit for Rat Urocortin
ELISA Kit for Rat Urocortin
CLIA Kit for Rat Urocortin
CLIA Kit for Rat Urocortin
CLIA Kit for Rat Urocortin
Polyclonal Antibody for Rat Urocortin
Polyclonal Antibody for Rat Urocortin
Polyclonal Antibody for Rat Urocortin
Monoclonal Antibody for Rat Urocortin
Monoclonal Antibody for Rat Urocortin
Monoclonal Antibody for Rat Urocortin
Protein for Rat Urocortin
Protein for Rat Urocortin
Protein for Rat Urocortin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor."
Vaughan J.M.
,
Donaldson C.J.
,
Bittencourt J.
,
Perrin M.H.
,
Lewis K.A.
,
Sutton S.W.
,
Chan R.
,
Turnbull A.
,
Lovejoy D.
,
Rivier C.
,
Rivier J.E.
,
Sawchenko P.
,
Vale W.W.
Nature378:287-292(1995)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
strain :
Sprague-Dawley .
2.
"Detection of rat urocortin in lymphoid tissues: implications for the functional assessment of urocortin as a novel neuro-immunomodulatory peptide."
Park J.H.
,
Lee Y.J.
,
Kim K.L.
Submitted (1998-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE
strain :
Lewis .
3.
"Urocortin 1 reduces food intake and ghrelin secretion via CRF(2) receptors."
Yakabi K.
,
Noguchi M.
,
Ohno S.
,
Ro S.
,
Onouchi T.
,
Ochiai M.
,
Takabayashi H.
,
Takayama K.
,
Harada Y.
,
Sadakane C.
,
Hattori T.
Am. J. Physiol.301:E72-82(2011)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION