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Index > Protein center > Unc5c(Gene name) > Rat
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  • Unc5c (Gene name),
  • Netrin receptor UNC5C (Protein name ),  UNC5C_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Unc5c(Unc5h3);
    Protein name:
    Netrin receptor UNC5C;
    Alternative:
    Protein unc-5 homolog C;Protein unc-5 homolog 3;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with the cytoplasmic part of DCC.
    Function:
    Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    931
    Sequence:
    50:
    MRKGLRATAA | RCGLGLGYLL | QMLVLPALAL | LSASGTGSAA | QDDDFFHELP | 
    100:
    ETFPSDPPEP | LPHFLIEPEE | AYIVKNKPVN | LYCKASPATQ | IYFKCNSEWV | 
    150:
    HQKDHVVDER | VDETSGLIVR | EVSIEISRQQ | VEELFGPEDY | WCQCVAWSSA | 
    200:
    GTTKSRKAYV | RIAYLRKTFE | QEPLGKEVSL | EQEVLLQCRP | PEGIPMAEVE | 
    250:
    WLKNEDIIDP | VEDRNFYITI | DHNLIIKQAR | LSDTANYTCV | AKNIVAKRKS | 
    300:
    TTATVIVYVN | GGWSTWAEWS | VCNSRCGRGY | QKRTRTCTNP | APLNGGAFCE | 
    350:
    GQSVQKIACT | TLCPVDGRWT | SWSKWSTCGT | ECTHWRRREC | TAPAPKNGGK | 
    400:
    DCDGLVLQSK | NCTDGLCMQA | APDSDDVALY | VGIVIAVTVC | LAITVVVALF | 
    450:
    VYRKNHRDFE | SNIIDSSALN | GGFQPVNIKA | ARQDLLAVPP | DLTSAAAMYR | 
    500:
    GPVYALHDVS | DKIPMTNSPI | LDPLPNLKIK | VYNSSGAVTP | QDDLAEFSSK | 
    550:
    LSPQMTQSLL | ENEALNLKNQ | SLARQTDPSC | TAFGTFNSLG | GHLIIPNSGV | 
    600:
    SLLIPAGAIP | QGRVYEMYVT | VHRKENMRPP | MEDSQTLLTP | VVSCGPPGAL | 
    650:
    LTRPVILTLH | HCADPNTEDW | KIQLKNQAVQ | GQWEDVVVVG | EENFTTPCYI | 
    700:
    QLDAEACHIL | TENLSTYALV | GQSTTKAAAK | RLKLAIFGPL | CCSSLEYSIR | 
    750:
    VYCLDDTQDA | LKEVLQLERQ | MGGQLLEEPK | ALHFKGSIHN | LRLSIHDITH | 
    800:
    SLWKSKLLAK | YQEIPFYHIW | SGSQRNLHCT | FTLERLSLNT | VELVCKLCVR | 
    850:
    QVEGEGQIFQ | LNCTVSEEPT | GIDLPLLDPA | STITTVTGPS | AFSIPLPIRQ | 
    900:
    KLCSSLDAPQ | TRGHDWRMLA | HKLNLDRYLN | YFATKSSPTG | VILDLWEAQN | 
    931:
    FPDGNLSMLA | AVLEEMGRHE | TVVSLAAEGQ | Y
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Netrin receptor UNC5C
    Cat.:
    E7813h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Netrin receptor UNC5C
    MSDS:
    Please sign in first.
    ELISA Kit for Rat Netrin receptor UNC5C
    Cat.:
    E7813m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat Netrin receptor UNC5C
    Cat.:
    E7813r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Netrin receptor UNC5C
    Cat.:
    U7813r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Netrin receptor UNC5C
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Netrin receptor UNC5C
    Cat.:
    U7813h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Netrin receptor UNC5C
    Cat.:
    U7813m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Netrin receptor UNC5C
    Polyclonal Antibody for Rat Netrin receptor UNC5C
    Cat.:
    P7813Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Netrin receptor UNC5C
    Cat.:
    P7813Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Netrin receptor UNC5C
    Monoclonal Antibody for Rat Netrin receptor UNC5C
    Monoclonal Antibody for Rat Netrin receptor UNC5C
    Monoclonal Antibody for Rat Netrin receptor UNC5C
    Monoclonal Antibody for Rat Netrin receptor UNC5C
    Protein for Rat Netrin receptor UNC5C
    Protein for Rat Netrin receptor UNC5C
    Protein for Rat Netrin receptor UNC5C
    Protein for Rat Netrin receptor UNC5C

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    References
    1. 1.
      "Rat neurological mutations cerebellar vermis defect and hobble are caused by mutations in the netrin-1 receptor gene Unc5h3."
      Kuramoto T. , Kuwamura M. , Serikawa T.
      Brain Res. Mol. Brain Res.122:103-108(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DISEASE
    2. 2.
      "Netrin-1 acts as a survival factor via its receptors UNC5H and DCC."
      Llambi F. , Causeret F. , Bloch-Gallego E. , Mehlen P.
      EMBO J.20:2715-2722(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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