ELL2 ELISA Kit for Human(Homo sapiens) | EIAab.comELL2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > ELL2(Gene name) > Human

ELL2 (Gene name),

RNA polymerase II elongation factor ELL2 (Protein name ), ELL2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ELL2;

Protein name:

RNA polymerase II elongation factor ELL2;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with EAF1 and EAF2.

Function:

Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

640

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

640:

KQSSPNYHEE | KYRCEYLHNK | LAHIKRLIGE | FDQQQAESWS |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF10390

String:

O00472

SMR:

O00472

MIM:

601874

KEGG:

hsa:22936

UniGene:

Hs.192221

STRING:

9606.ENSP00000237853

Uniprot:

O00472

FOR

ELISA Kit for Human RNA polymerase II elongation factor ELL2

CLIA Kit for Human RNA polymerase II elongation factor ELL2

Polyclonal Antibody for Human RNA polymerase II elongation factor ELL2

Monoclonal Antibody for Human RNA polymerase II elongation factor ELL2

Protein for Human RNA polymerase II elongation factor ELL2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"ELL2, a new member of an ELL family of RNA polymerase II elongation factors."
Shilatifard A. , Duan D.R. , Haque D. , Florence C. , Schubach W.H. , Conaway J.W. , Conaway R.C.
Proc. Natl. Acad. Sci. U.S.A.94:3639-3643(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-298
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
3.

"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J. , Martin J. , Terry A. , Couronne O. , Grimwood J. , Lowry S. , Gordon L.A. , Scott D. , Xie G. , Huang W. , Hellsten U. , Tran-Gyamfi M. , She X. , Prabhakar S. , Aerts A. , Altherr M. , Bajorek E. , Black S. , more...
Nature431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT THR-298
tissue: Testis.
5.

"EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein."
Simone F. , Polak P.E. , Kaberlein J.J. , Luo R.T. , Levitan D.A. , Thirman M.J.
Blood98:201-209(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EAF1
6.

"ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties."
Simone F. , Luo R.T. , Polak P.E. , Kaberlein J.J. , Thirman M.J.
Blood101:2355-2362(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EAF2
7.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-580;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
8.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
9.

"HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription."
He N. , Liu M. , Hsu J. , Xue Y. , Chou S. , Burlingame A. , Krogan N.J. , Alber T. , Zhou Q.
Mol. Cell38:428-438(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE SEC COMPLEX
10.

"AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia."
Lin C. , Smith E.R. , Takahashi H. , Lai K.C. , Martin-Brown S. , Florens L. , Washburn M.P. , Conaway J.W. , Conaway R.C. , Shilatifard A.
Mol. Cell37:429-437(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE SEC COMPLEX
11.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-503;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
12.

"The little elongation complex regulates small nuclear RNA transcription."
Smith E.R. , Lin C. , Garrett A.S. , Thornton J. , Mohaghegh N. , Hu D. , Jackson J. , Saraf A. , Swanson S.K. , Seidel C. , Florens L. , Washburn M.P. , Eissenberg J.C. , Shilatifard A.
Mol. Cell44:954-965(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE SEC COMPLEX;IDENTIFICATION IN THE LEC COMPLEX
13.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-503;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"The ubiquitin ligase Siah1 controls ELL2 stability and formation of super elongation complexes to modulate gene transcription."
Liu M. , Hsu J. , Chan C. , Li Z. , Zhou Q.
Mol. Cell46:325-334(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION
15.

"The super elongation complex (SEC) family in transcriptional control."
Luo Z. , Lin C. , Shilatifard A.
Nat. Rev. Mol. Cell Biol.13:543-547(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON THE SUPER ELONGATION COMPLEX
16.

"HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold."
Chou S. , Upton H. , Bao K. , Schulze-Gahmen U. , Samelson A.J. , He N. , Nowak A. , Lu H. , Krogan N.J. , Zhou Q. , Alber T.
Proc. Natl. Acad. Sci. U.S.A.110:E123-E131(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
17.

"Solution structure of the ELL_N2 domain of target of RNA polymerase II elongation factor ELL2."
RIKEN structural genomics initiative (RSGI)
Submitted (2007-06) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 197-292

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