Tceb1 ELISA Kit for Mouse(Mus musculus) | EIAab.comTceb1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Tceb1(Gene name) > Mouse

Tceb1 (Gene name),

Transcription elongation factor B polypeptide 1 (Protein name ), ELOC_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Tceb1;

Protein name:

Transcription elongation factor B polypeptide 1;

Alternative:

Elongin-C(EloC);Elongin 15 kDa subunit;SIII p15;RNA polymerase II transcription factor SIII subunit C;Stromal membrane-associated protein SMAP1B homolog;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterotrimer of an A (A1, A2 or A3), B and C subunit. Part of E3 ubiquitin ligase complexes with CUL5 or CUL2, RBX1 and a substrate adapter protein that can be either SOCS1, TCEB3, VHL or WSB1. The elongin BC complex is part of a complex with hydroxylated HIF1A. Interacts with VHL. Interacts with TMF1.

Function:

The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

112

Sequence:

50:

100:

112:

LELLMAANFL | DC

3D Structure:

N/A