Tceb1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comTceb1 ELISA Kit for Rat(Rattus norvegicus)

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Tceb1 (Gene name),

Transcription elongation factor B polypeptide 1 (Protein name ), ELOC_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Tceb1;

Protein name:

Transcription elongation factor B polypeptide 1;

Alternative:

Elongin-C(EloC);Elongin 15 kDa subunit;SIII p15;RNA polymerase II transcription factor SIII subunit C;Stromal membrane-associated protein SMAP1B homolog;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Heterotrimer of an A (A1, A2 or A3), B and C subunit. Part of E3 ubiquitin ligase complexes with CUL5 or CUL2, RBX1 and a substrate adapter protein that can be either SOCS1, TCEB3, VHL or WSB1. The elongin BC complex is part of a complex with hydroxylated HIF1A. Interacts with VHL. Interacts with TMF1.

Function:

The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

112

Sequence:

50:

100:

112:

LELLMAANFL | DC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.38378

UniGene:

Rn.48516

SMR:

P83941

Pfam:

PF03931

STRING:

10116.ENSRNOP00000000132

String:

P83941

KEGG:

rno:64525

Uniprot:

P83941

FOR

ELISA Kit for Rat Transcription elongation factor B polypeptide 1

CLIA Kit for Rat Transcription elongation factor B polypeptide 1

Polyclonal Antibody for Rat Transcription elongation factor B polypeptide 1

Monoclonal Antibody for Rat Transcription elongation factor B polypeptide 1

Protein for Rat Transcription elongation factor B polypeptide 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of an essential subunit of RNA polymerase II elongation factor SIII."
Garrett K.P. , Tan S. , Bradsher J.N. , Lane W.S. , Conaway J.W. , Conaway R.C.
Proc. Natl. Acad. Sci. U.S.A.91:5237-5241(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Brain.
tissue: Liver.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pituitary.
3.

"Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase."
Kamura T. , Koepp D.M. , Conrad M.N. , Skowyra D. , Moreland R.J. , Iliopoulos O. , Lane W.S. , Kaelin W.G. Jr. , Elledge S.J. , Conaway R.C. , Harper J.W. , Conaway J.W.
Science284:657-661(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH TCEB2; VHL; CUL2 AND RBX1

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