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Index > Protein center > Elovl2(Gene name) > Mouse
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  • Elovl2 (Gene name),
  • Elongation of very long chain fatty acids protein 2 (Protein name ),  ELOV2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Elovl2(Ssc2);
    Protein name:
    Elongation of very long chain fatty acids protein 2;
    Alternative:
    ELOVL fatty acid elongase 2(ELOVL FA elongase 2);3-keto acyl-CoA synthase Elovl2;Very-long-chain 3-oxoacyl-CoA synthase 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (n-6 and n-3 C18-, C20-and C22-PUFA). Essential for the formation of C24:5(n-6) up to C30:5(n-6) PUFAs in testis, these fatty acids being indispensable for normal spermatogenesis and fertility.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    292
    Sequence:
    50:
    MEQLKAFDNE | VNAFLDNMFG | PRDSRVRGWF | LLDSYLPTFI | LTITYLLSIW | 
    100:
    LGNKYMKNRP | ALSLRGILTL | YNLAITLLSA | YMLVELILSS | WEGGYNLQCQ | 
    150:
    NLDSAGEGDV | RVAKVLWWYY | FSKLVEFLDT | IFFVLRKKTN | QITFLHVYHH | 
    200:
    ASMFNIWWCV | LNWIPCGQSF | FGPTLNSFIH | ILMYSYYGLS | VFPSMHKYLW | 
    250:
    WKKYLTQAQL | VQFVLTITHT | LSAVVKPCGF | PFGCLIFQSS | YMMTLVILFL | 
    292:
    NFYIQTYRKK | PVKKELQEKE | VKNGFPKAHL | IVANGMTDKK | AQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Elongation of very long chain fatty acids protein 2
    ELISA Kit for Mouse Elongation of very long chain fatty acids protein 2
    ELISA Kit for Mouse Elongation of very long chain fatty acids protein 2
    CLIA Kit for Mouse Elongation of very long chain fatty acids protein 2
    CLIA Kit for Mouse Elongation of very long chain fatty acids protein 2
    CLIA Kit for Mouse Elongation of very long chain fatty acids protein 2
    Polyclonal Antibody for Mouse Elongation of very long chain fatty acids protein 2
    Polyclonal Antibody for Mouse Elongation of very long chain fatty acids protein 2
    Polyclonal Antibody for Mouse Elongation of very long chain fatty acids protein 2
    Monoclonal Antibody for Mouse Elongation of very long chain fatty acids protein 2
    Monoclonal Antibody for Mouse Elongation of very long chain fatty acids protein 2
    Monoclonal Antibody for Mouse Elongation of very long chain fatty acids protein 2
    Protein for Mouse Elongation of very long chain fatty acids protein 2
    Protein for Mouse Elongation of very long chain fatty acids protein 2
    Protein for Mouse Elongation of very long chain fatty acids protein 2

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    Precision
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    Linearity
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    References
    1. 1.
      "Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids."
      Tvrdik P. , Westerberg R. , Silve S. , Asadi A. , Jakobsson A. , Cannon B. , Loison G. , Jacobsson A.
      J. Cell Biol.149:707-718(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      strain: BALB/c.
      tissue: Liver.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Testis.
    3. 3.
      "Identification and expression of mammalian long-chain PUFA elongation enzymes."
      Leonard A.E. , Kelder B. , Bobik E.G. , Chuang L.-T. , Lewis C.J. , Kopchick J.J. , Mukerji P. , Huang Y.-S.
      Lipids37:733-740(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;PATHWAY;TISSUE SPECIFICITY
    4. 4.
      "ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice."
      Zadravec D. , Tvrdik P. , Guillou H. , Haslam R. , Kobayashi T. , Napier J.A. , Capecchi M.R. , Jacobsson A.
      J. Lipid Res.52:245-255(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;PATHWAY
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