Elovl3 ELISA Kit for Mouse(Mus musculus) | EIAab.comElovl3 ELISA Kit for Mouse(Mus musculus)

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Elovl3 (Gene name),

Elongation of very long chain fatty acids protein 3 (Protein name ), ELOV3_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Elovl3(Cig30);

Protein name:

Elongation of very long chain fatty acids protein 3;

Alternative:

CIN-2;3-keto acyl-CoA synthase Elovl3;ELOVL fatty acid elongase 3(ELOVL FA elongase 3);Cold-inducible glycoprotein of 30 kDa;Very-long-chain 3-oxoacyl-CoA synthase 3;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs) of up to 24 carbon atoms. Participates in the formation of certain VLCFA and triglycerides in certain cells of the hair follicles and the sebaceous glands, required for skin barrier function. Critical enzyme for lipid accumulation and metabolic activity in brown adipocytes during the early phase of the tissue recruitment. Play a role in lipid storage and in resistance to diet-induced obesity.

Subcellular Location:

Endoplasmic reticulum membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

271

Sequence:

50:

100:

150:

200:

250:

271:

FAHFFHRAYL | RPKGKVASKS | Q

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.21806

KEGG:

mmu:12686

STRING:

10090.ENSMUSP00000036357

String:

O35949

Pfam:

PF01151

Uniprot:

O35949

FOR

ELISA Kit for Mouse Elongation of very long chain fatty acids protein 3

CLIA Kit for Mouse Elongation of very long chain fatty acids protein 3

Polyclonal Antibody for Mouse Elongation of very long chain fatty acids protein 3

Monoclonal Antibody for Mouse Elongation of very long chain fatty acids protein 3

Protein for Mouse Elongation of very long chain fatty acids protein 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cig30, a mouse member of a novel membrane protein gene family, is involved in the recruitment of brown adipose tissue."
Tvrdik P. , Asadi A. , Kozak L.P. , Nedergaard J. , Cannon B. , Jacobsson A.
J. Biol. Chem.272:31738-31746(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];GLYCOSYLATION AT ASN-6;TISSUE SPECIFICITY
strain: C57BL/6.
tissue: Brown adipose tissue.
2.

"Cig30 and Pitx3 genes are arranged in a partially overlapping tail-to-tail array resulting in complementary transcripts."
Tvrdik P. , Asadi A. , Kozak L.P. , Nuglozeh E. , Parente F. , Nedergaard J. , Jacobsson A.
J. Biol. Chem.274:26387-26392(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: 129/SvJ.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Liver.
4.

"N-tail translocation in a eukaryotic polytopic membrane protein: synergy between neighboring transmembrane segments."
Monne M. , Gafvelin G. , Nilsson R. , von Heijne G.
Eur. J. Biochem.263:264-269(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-6;SUBCELLULAR LOCATION
5.

"Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids."
Tvrdik P. , Westerberg R. , Silve S. , Asadi A. , Jakobsson A. , Cannon B. , Loison G. , Jacobsson A.
J. Cell Biol.149:707-718(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
strain: BALB/c.
tissue: Liver.
6.

"Role for ELOVL3 and fatty acid chain length in development of hair and skin function."
Westerberg R. , Tvrdik P. , Unden A.B. , Mansson J.E. , Norlen L. , Jakobsson A. , Holleran W.H. , Elias P.M. , Asadi A. , Flodby P. , Toftgard R. , Capecchi M.R. , Jacobsson A.
J. Biol. Chem.279:5621-5629(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY
7.

"ELOVL3 is an important component for early onset of lipid recruitment in brown adipose tissue."
Westerberg R. , Mansson J.E. , Golozoubova V. , Shabalina I.G. , Backlund E.C. , Tvrdik P. , Retterstol K. , Capecchi M.R. , Jacobsson A.
J. Biol. Chem.281:4958-4968(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
8.

"Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity."
Zadravec D. , Brolinson A. , Fisher R.M. , Carneheim C. , Csikasz R.I. , Bertrand-Michel J. , Boren J. , Guillou H. , Rudling M. , Jacobsso A.
FASEB J.24:4366-4377(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE

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