Gene name:
Ikbkap (Elp1;Ikap) ;
Protein name:
Elongator complex protein 1 (ELP1) ;
Alternative:
IkappaB kinase complex-associated protein (IKK complex-associated protein) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts preferentially with MAP3K14/NIK followed by IKK-alpha and IKK-beta. Component of the RNA polymerase II elongator complex (Elongator), which consists of IKBKAP/ELP1, STIP1/ELP2, ELP3, ELP4, and two yet unidentified proteins. Elongator associates with the C-terminal domain (CTD) of Pol II largest subunit. Interacts with ELP3.
Function:
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
Subcellular Location:
Cytoplasm
Nucleus
Protein Attributes:
50:
MRNLKLHRTL | EFRDIQAPGK | PQCFCLRAEQ | GTVLIGSERG | LTEVDPVRRE |
100:
VKTEISLVAE | GFLPEDGSGC | IVGIQDLLDQ | ESVCVATASG | DVIVCNLSTQ |
150:
QLECVGSVAS | GISVMSWSPD | QELLLLATAQ | QTLIMMTKDF | EVIAEEQIHQ |
200:
DDFGEGKFVT | VGWGSKQTQF | HGSEGRPTAF | PVQLPENALP | WDDRRPHITW |
250:
RGDGQYFAVS | VVCRQTEARK | IRVWNREFAL | QSTSESVPGL | GPALAWKPSG |
300:
SLIASTQDKP | NQQDVVFFEK | NGLLHGHFTL | PFLKDEVKVN | DLLWNADSSV |
350:
LAIWLEDLPK | EDSSTLKSYV | QLWTVGNYHW | YLKQSLPFST | TGKNQIVSLL |
400:
WDPVTPCRLH | VLCTGWRYLC | CDWHWTTDRS | SGNSANDLAN | VAVIDGNRVL |
450:
VTVFRQTVVP | PPMCTYRLLI | PHPVNQVIFS | AHLGNDLAVL | DASNQISVYK |
500:
CGDKPNMDST | VKLGAVGGNG | FKVPLTTPHL | EKRYSIQFGN | NEEEEEEEVN |
550:
ALQLSFLTWV | EDDTFLAISY | SHSSSQSIIH | HLTVTHSEVD | EEQGQLDVSS |
600:
SVTVDGVVIG | LCCCSKTKSL | AVQLADGQVL | KYLWESPSLA | VEPWKNSEGI |
650:
PVRFVHPCTQ | MEVATIGGEE | CVLGLTDRCR | FFINDTEVAS | NITSFAVCDD |
700:
FLLVTTHSHT | CQVFSLSGAS | LKMLQAALSG | SHEASGEILR | KVERGSRIVT |
750:
VVPQDTKLIL | QMPRGNLEVV | HHRALVLAQI | RKWLDKLMFK | EAFECMRKLR |
800:
INLNLIHDHN | PKVFLENVET | FVKQIDSVNH | INLFFTELRE | EDVTKTMYPP |
850:
PITKSVQVST | HPDGKKLDLI | CDAMRAAMEA | INPRKFCLSI | LTSHVKKTTP |
900:
ELEIVLQKVQ | ELQGNLPFDP | ESVSVEEALK | YLLLLVDVNE | LFNHSLGTYD |
950:
FNLVLMVAEK | SQKDPKEYLP | FLNTLKKMET | NYQRFTIDKY | LKRYEKALGH |
1000:
LSKCGPEYFT | ECLNLIKDKN | LYKEALKLYR | PDSPQYQAVS | MAYGEHLMQE |
1050:
HLYEPAGLVF | ARCGAQEKAL | EAFLACGSWQ | QALCVAAQLQ | MSKDKVAGLA |
1100:
RTLAGKLVEQ | RKHSEAATVL | EQYAQDYEEA | VLLLLEGSAW | EEALRLVYKY |
1150:
DRVDIIETSV | KPSILEAQKN | YMDFLDSETA | TFIRHKNRLQ | VVRALRRQAP |
1200:
QVHVDHEVAH | GPESDLFSET | SSIMSGSEMS | GRYSHSNSRI | SARSSKNRRK |
1250:
AERKKHSLKE | GSPLEGLALL | EALSEVVQSV | EKLKDEVRAI | LKVLFLFEFE |
1300:
EQAKELQRAF | ESTLQLMERA | VPEIWTPAGQ | QSSTTPVLGP | SSTANSITAS |
1333:
YQQQKTCVPA | LDAGVYMPPK | MDPRSQWKLS | LLE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rabbit
Rat
Mouse
Polyclonal Antibody for Mouse ELP1
Polyclonal Antibody for Mouse ELP1
Polyclonal Antibody for Mouse ELP1
Polyclonal Antibody for Mouse ELP1
Monoclonal Antibody for Mouse ELP1
Monoclonal Antibody for Mouse ELP1
Monoclonal Antibody for Mouse ELP1
Monoclonal Antibody for Mouse ELP1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];DEVELOPMENTAL STAGE;TISSUE SPECIFICITY
strain :
BALB/c .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
129/SvJ .
tissue :
Spleen .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 X CBA .
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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C57BL/6J .
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Cerebellum .
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Head .
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PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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C57BL/6 .
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Eye .
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"Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin."
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[
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN NEUROGENESIS;SUBCELLULAR LOCATION
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PubMed ]
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION