Gene name:
IKBKAP (ELP1;IKAP) ;
Protein name:
Elongator complex protein 1 (ELP1) ;
Alternative:
IkappaB kinase complex-associated protein (IKK complex-associated protein) ;
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
Interacts preferentially with MAP3K14/NIK followed by IKK-alpha and IKK-beta. Component of the RNA polymerase II elongator complex (Elongator), which consists of IKBKAP/ELP1, STIP1/ELP2, ELP3, ELP4, and two yet unidentified proteins. Elongator associates with the C-terminal domain (CTD) of Pol II largest subunit. Interacts with ELP3.
Function:
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
Subcellular Location:
Cytoplasm
Nucleus
Protein Attributes:
50:
MRNLKLLQTL | EFKDIQAPGK | PQCFSLRTEP | GTVLIGSEHG | LIEVDPVTRE |
100:
VKNEIPLVAE | GFLPEDKSGC | IVGIQDLLDQ | ESVCIATASG | DVILCNLSTH |
150:
QLECVGSVAS | GISVMSWSPD | QELVLLATGQ | QTLIMMTKDF | EPIMEQQIHQ |
200:
DDFGESKFIT | VGWGKKETQF | HGSEGRQAAF | QIQTHESALP | WDDHRPRVTW |
250:
RGDGQFFAVS | VVCPETGARK | VRVWNREFAL | QSTSEPVPGL | GPALAWKPSG |
300:
SLIASTQNKP | NQQDVVFFEK | NGLLHGQFTL | PFLKDEVKVN | DLLWNADSSV |
350:
LAVWLEDLQR | EEDSVLKTYV | QLWTVGNYHW | YLNECLPFST | YGKSKIVSLM |
400:
WDPVIPYRLH | VLCQGWHYLC | YDWRWTTDRS | SGDNESDLAN | VAVIDGNRIL |
450:
VTVFQQTVVP | PPMCTYRLLL | PHPVNQVTFC | ALPKKSNDLA | VLDASNQISV |
500:
YKCGDSPSMD | PTVKLGAVGG | NGFKVSLRTP | HLEKRYKIQF | ESNEDQETNP |
550:
LKLSLLSWIE | EDIFLAICHS | QCSPQQSVIH | RLTVVPCEVD | EEQGQLSVSS |
600:
SISVDGIIIS | MCCNSKTKSV | ALQLADGQIL | KYIWESPSLA | VEPWKNPGGF |
650:
PIQFPYPCIQ | TELAMIGGEE | CVLGLTDRCR | FFINDTEVAS | NITSFAVYDE |
700:
FLLLTTHSHT | CQCYCLKDAS | IKTLQAGLSS | SHVSNGEILR | KVERGSRIVT |
750:
VVPQDTKLIL | QMPRGNLEVV | HHRALVLAQI | RKWLDKIMFK | EAFECMRKLR |
800:
INLNLIHDHN | PEVFLQNVET | FIRQIDCVNH | INLFFTELKE | EDVTKTMYPP |
850:
PVPSSVQQSR | DPGGTKLDLI | CDALRVAMEN | INPHKYCLPI | LTSHVKKTTP |
900:
ELEIVLQKVH | ELQGNAPSDP | DAVSAEEALK | YLLLLVDVNE | LYDHSLGTYD |
950:
FDLVLMVAEK | SQKDPKEYLP | FLNTLKKMET | NYQRFTIDKY | LKRYEKAIGH |
1000:
LSKCGPEYFS | ECLNLIKDKN | LYNEALKLYP | PTSQEYKDIS | IAYGEHLMEE |
1050:
HQYEPAGLVF | ARCGAHEKAL | SAFLTCGSWQ | QTLCMAAQLN | MTEEQLAGLG |
1100:
RTLAGKLAEQ | RKHSDAAIVL | EQYTQDYEEA | VLLLLEGAAW | EEALRLVYKY |
1150:
NRLDIIETNI | KPSILEAYKN | YMAFLESQSA | TFSRHKERLL | EVRELKERAQ |
1200:
QVDLDDEMPH | GQEADLFSET | SSIVSGSEMS | SKYSHSNSRI | SARSSKNRRK |
1250:
AERKKHSLKE | GSPLEDLALL | EALNEVVQSL | DKLKDEVYRI | LKVLFLFEFD |
1300:
EQGRELQKTF | QDTLQLVERS | LPEIWTLTYQ | QNSAMPVLGP | SSTANSIMAS |
1333:
YQQQKTSVPV | LDAELFVPPK | INRKTQWKLS | LLE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rabbit
Rat
Mouse
ELISA Kit for Rabbit ELP1
ELISA Kit for Rabbit ELP1
ELISA Kit for Rabbit ELP1
ELISA Kit for Rabbit ELP1
Polyclonal Antibody for Rabbit ELP1
Polyclonal Antibody for Rabbit ELP1
Polyclonal Antibody for Rabbit ELP1
Polyclonal Antibody for Rabbit ELP1
Monoclonal Antibody for Rabbit ELP1
Monoclonal Antibody for Rabbit ELP1
Monoclonal Antibody for Rabbit ELP1
Monoclonal Antibody for Rabbit ELP1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]