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Index > Protein center > ELP5(Gene name) > Human
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  • ELP5 (Gene name),
  • Elongator complex protein 5 (Protein name ),  ELP5_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ELP5(HSPC002;MSTP071;C17orf81;DERP6);
    Protein name:
    Elongator complex protein 5;
    Alternative:
    S-phase 2 protein;Dermal papilla-derived protein 6;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of the RNA polymerase II elongator complex (Elongator), which consists of IKBKAP/ELP1, STIP1/ELP2, ELP3, ELP4, ELP5 and ELP6; in the complex, is required for optimal binding of ELP3 to ELP4.
    Function:
    Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration (By similarity). May be involved in TP53-mediated transcriptional regulation.
    Subcellular Location:
    Nucleus Cytoplasm
    Protein Attributes:
    Sequence length:
    316
    Sequence:
    50:
    MTPSEGARAG | TGRELEMLDS | LLALGGLVLL | RDSVEWEGRS | LLKALVKKSA | 
    100:
    LCGEQVHILG | CEVSEEEFRE | GFDSDINNRL | VYHDFFRDPL | NWSKTEEAFP | 
    150:
    GGPLGALRAM | CKRTDPVPVT | IALDSLSWLL | LRLPCTTLCQ | VLHAVSHQDS | 
    200:
    CPGDSSSVGK | VSVLGLLHEE | LHGPGPVGAL | SSLAQTEVTL | GGTMGQASAH | 
    250:
    ILCRRPRQRP | TDQTQWFSIL | PDFSLDLQEG | PSVESQPYSD | PHIPPVDPTT | 
    300:
    HLTFNLHLSK | KEREARDSLI | LPFQFSSEKQ | QALLRPRPGQ | ATSHIFYEPD | 
    316:
    AYDDLDQEDP | DDDLDI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Elongator complex protein 5
    ELISA Kit for Human Elongator complex protein 5
    ELISA Kit for Human Elongator complex protein 5
    CLIA Kit for Human Elongator complex protein 5
    CLIA Kit for Human Elongator complex protein 5
    CLIA Kit for Human Elongator complex protein 5
    Polyclonal Antibody for Human Elongator complex protein 5
    Polyclonal Antibody for Human Elongator complex protein 5
    Polyclonal Antibody for Human Elongator complex protein 5
    Monoclonal Antibody for Human Elongator complex protein 5
    Monoclonal Antibody for Human Elongator complex protein 5
    Monoclonal Antibody for Human Elongator complex protein 5
    Protein for Human Elongator complex protein 5
    Protein for Human Elongator complex protein 5
    Protein for Human Elongator complex protein 5

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and characterization of the human gene DERP6, which activates transcriptional activities of p53."
      Yuan J. , Tang W. , Luo K. , Chen X. , Gu X. , Wan B. , Yu L.
      Mol. Biol. Rep.33:151-158(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION
    2. 2.
      "Molecular cloning of a dermal papilla derived gene."
      Ikeda A. , Yoshimoto M.
      Submitted (1998-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT LYS-14
      tissue: Hair follicle dermal papilla.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Hippocampus.
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT TYR-303
      tissue: Placenta.
    6. 7.
      "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
      Zhang Q.-H. , Ye M. , Wu X.-Y. , Ren S.-X. , Zhao M. , Zhao C.-J. , Fu G. , Shen Y. , Fan H.-Y. , Lu G. , Zhong M. , Xu X.-R. , Han Z.-G. , Zhang J.-W. , Tao J. , Huang Q.-H. , Zhou J. , Hu G.-X. , more...
      Genome Res.10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 10-316 (ISOFORM 3)
      tissue: Umbilical cord blood.
    7. 8.
      Zhao B. , Xu Y.Y. , Liu Y.Q. , Wang X.Y. , Liu B. , Sheng H. , Ye J. , Song L. , Gao Y. , Zhang C.L. , Zhang J. , Gao R.L. , Wu Q.Y. , Hui R.T.
      Submitted (1999-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 24-316 (ISOFORM 2)
      tissue: Aorta.
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 149-316 (ISOFORM 4)
      tissue: Amygdala.
    9. 10.
      "DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator."
      Close P. , Gillard M. , Ladang A. , Jiang Z. , Papuga J. , Hawkes N. , Nguyen L. , Chapelle J.P. , Bouillenne F. , Svejstrup J. , Fillet M. , Chariot A.
      J. Biol. Chem.287:32535-32545(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE RNA POLYMERASE II ELONGATOR COMPLEX;SUBCELLULAR LOCATION;IDENTIFICATION BY MASS SPECTROMETRY
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