Gene name:
Elp5 (Derp6;Rai12) ;
Protein name:
Elongator complex protein 5 ;
Alternative:
Retinoic acid-induced protein 12 ;Dermal papilla-derived protein 6 homolog ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Component of the RNA polymerase II elongator complex (Elongator), which consists of IKBKAP/ELP1, STIP1/ELP2, ELP3, ELP4, ELP5 and ELP6; in the complex, is required for optimal binding of ELP3 to ELP4.
Function:
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. May be involved in TP53-mediated transcriptional regulation.
Subcellular Location:
Nucleus
Cytoplasm
Protein Attributes:
50:
MPRLLSGDDI | RRRPEASEML | DSLLATGGLV | LLRDSVEWEG | RGLLKALIKK |
100:
SALRGEQVHV | LGCEVSEEEF | REGLGSDVNS | RLVYHDLFRD | PLNWSQPGEA |
150:
APEGPLKALR | SMCRRTDRGS | VTIALDSLSW | LLCHIPCVTL | CQALHALSQR |
200:
NVDPGDNPLI | EQVRVLGLLH | EELHGPGPVG | AVSSLAHTEV | TLSGKMDQTS |
250:
ASILCRRPQQ | RATYQTWWFS | ILPDFSLDLH | EGLPLHSELH | RDPHTTQVDP |
300:
ASHLTFNLHL | SKKEREAKDS | LTLPFQFSSE | KQQALLHPVP | GQTTGRIFYE |
318:
PDAFDDVDQE | DPDDDLDI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Rat Elongator complex protein 5
ELISA Kit for Rat Elongator complex protein 5
ELISA Kit for Rat Elongator complex protein 5
CLIA Kit for Rat Elongator complex protein 5
CLIA Kit for Rat Elongator complex protein 5
CLIA Kit for Rat Elongator complex protein 5
Polyclonal Antibody for Rat Elongator complex protein 5
Polyclonal Antibody for Rat Elongator complex protein 5
Polyclonal Antibody for Rat Elongator complex protein 5
Monoclonal Antibody for Rat Elongator complex protein 5
Monoclonal Antibody for Rat Elongator complex protein 5
Monoclonal Antibody for Rat Elongator complex protein 5
Protein for Rat Elongator complex protein 5
Protein for Rat Elongator complex protein 5
Protein for Rat Elongator complex protein 5
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Cloning and characterization of a novel rat DERP6 gene."
Yuan J.
,
Shan Y.X.
Submitted (2004-05) to the EMBL/GenBank/DDBJ databases
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]