Ahctf1 ELISA Kit for Mouse(Mus musculus) | EIAab.comAhctf1 ELISA Kit for Mouse(Mus musculus)

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Ahctf1 (Gene name),

Protein ELYS (Protein name ), ELYS_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ahctf1(Elys);

Protein name:

Protein ELYS;

Alternative:

Protein MEL-28;Embryonic large molecule derived from yolk sac;Putative AT-hook-containing transcription factor 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Associates with the Nup107-160 subcomplex of the NPC.

Function:

Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis (By similarity). Has also been proposed to function as a transcription factor which may play a specific role in hematopoietic tissues (PubMed:11952839).

Subcellular Location:

Chromosome centromere kinetochore Nucleus nucleoplasm Nucleus nuclear pore complex Nucleus matrix Cytoplasm Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107-160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase.

Protein Attributes:

Sequence length:

2243

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ASPVDEIKTG | KPRKTAEIAG | KTLGRGRKKP | SSFPKQILRR | KML

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:226747

Pfam:

PF13934

UniGene:

Mm.128165

String:

Q8CJF7

SMR:

Q8CJF7

STRING:

10090.ENSMUSP00000027768

Uniprot:

Q8CJF7

FOR

ELISA Kit for Mouse Protein ELYS

CLIA Kit for Mouse Protein ELYS

Polyclonal Antibody for Mouse Protein ELYS

Monoclonal Antibody for Mouse Protein ELYS

Protein for Mouse Protein ELYS

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues."
Kimura N. , Takizawa M. , Okita K. , Natori O. , Igarashi K. , Ueno M. , Nakashima K. , Nobuhisa I. , Taga T.
Genes Cells7:435-446(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;SUBCELLULAR LOCATION
strain: C57BL/6.
tissue: Yolk sac.
2.

"Genomic organization and characterization of the mouse ELYS gene."
Okita K. , Takizawa M. , Ueno M. , Kimura N. , Nobuhisa I. , Taga T.
Biochem. Biophys. Res. Commun.305:327-332(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: C57BL/6.
tissue: Liver.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
4.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2082-2243
strain: C57BL/6J.
tissue: Fetal head.
5.

"Targeted disruption of the mouse ELYS gene results in embryonic death at peri-implantation development."
Okita K. , Kiyonari H. , Nobuhisa I. , Kimura N. , Aizawa S. , Taga T.
Genes Cells9:1083-1091(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE
6.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1080 AND SER-1218;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
7.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1381;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.

"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-2221;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
9.

"Structural and functional studies of the 252 kDa nucleoporin ELYS reveal distinct roles for its three tethered domains."
Bilokapic S. , Schwartz T.U.
Structure21:572-580(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 1-494;REPEATS;SUBCELLULAR LOCATION;MUTAGENESIS OF TYR-284 AND 272-PHE--ARG-280

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