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Index > Protein center > EMILIN1(Gene name) > Human
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  • EMILIN1 (Gene name),
  • EMILIN-1 (Protein name ),  EMIL1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    EMILIN1(EMI);
    Protein name:
    EMILIN-1;
    Alternative:
    Elastin microfibril interface-located protein 1(Elastin microfibril interfacer 1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotrimer associated through a moderately stable interaction of the C-terminal globular C1q domains, allowing the nucleation of the triple helix and then a further quaternary assembly to higher order polymers via intermolecular disulfide bonds. Interacts with EMILIN2.
    Function:
    May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
    Subcellular Location:
    Secreted extracellular space extracellular matrix Found mainly at the interface between amorphous elastin and microfibrils.
    Protein Attributes:
    Sequence length:
    1016
    Sequence:
    50:
    MAPRTLWSCY | LCCLLTAAAG | AASYPPRGFS | LYTGSSGALS | PGGPQAQIAP | 
    100:
    RPASRHRNWC | AYVVTRTVSC | VLEDGVETYV | KYQPCAWGQP | QCPQSIMYRR | 
    150:
    FLRPRYRVAY | KTVTDMEWRC | CQGYGGDDCA | ESPAPALGPA | SSTPRPLAQP | 
    200:
    ARPNLSGSSA | GSPLSGLGGE | GPGESEKVQQ | LEEQVQSLTK | ELQGLRGVLQ | 
    250:
    GLSGRLAEDV | QRAVETAFNG | RQQPADAAAR | PGVHETLNEI | QHQLQLLDTR | 
    300:
    VSTHDQELGH | LNNHHGGSSS | SGGSRAPAPA | SAPPGPSEEL | LRQLEQRLQE | 
    350:
    SCSVCLAGLD | GFRRQQQEDR | ERLRAMEKLL | ASVEERQRHL | AGLAVGRRPP | 
    400:
    QECCSPELGR | RLAELERRLD | VVAGSVTVLS | GRRGTELGGA | AGQGGHPPGY | 
    450:
    TSLASRLSRL | EDRFNSTLGP | SEEQEESWPG | APGGLSHWLP | AARGRLEQLG | 
    500:
    GLLANVSGEL | GGRLDLLEEQ | VAGAMQACGQ | LCSGAPGEQD | SQVSEILSAL | 
    550:
    ERRVLDSEGQ | LRLVGSGLHT | VEAAGEARQA | TLEGLQEVVG | RLQDRVDAQD | 
    600:
    ETAAEFTLRL | NLTAARLGQL | EGLLQAHGDE | GCGACGGVQE | ELGRLRDGVE | 
    650:
    RCSCPLLPPR | GPGAGPGVGG | PSRGPLDGFS | VFGGSSGSAL | QALQGELSEV | 
    700:
    ILSFSSLNDS | LNELQTTVEG | QGADLADLGA | TKDRIISEIN | RLQQEATEHA | 
    750:
    TESEERFRGL | EEGQAQAGQC | PSLEGRLGRL | EGVCERLDTV | AGGLQGLREG | 
    800:
    LSRHVAGLWA | GLRETNTTSQ | MQAALLEKLV | GGQAGLGRRL | GALNSSLQLL | 
    850:
    EDRLHQLSLK | DLTGPAGEAG | PPGPPGLQGP | PGPAGPPGSP | GKDGQEGPIG | 
    900:
    PPGPQGEQGV | EGAPAAPVPQ | VAFSAALSLP | RSEPGTVPFD | RVLLNDGGYY | 
    950:
    DPETGVFTAP | LAGRYLLSAV | LTGHRHEKVE | AVLSRSNQGV | ARVDSGGYEP | 
    1000:
    EGLENKPVAE | SQPSPGTLGV | FSLILPLQAG | DTVCVDLVMG | QLAHSEEPLT | 
    1016:
    IFSGALLYGD | PELEHA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    SMR:
    String:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human EMILIN-1
    Cat.:
    E0415h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human EMILIN-1
    Cat.:
    E0415m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human EMILIN-1
    Cat.:
    U0415h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human EMILIN-1
    Cat.:
    U0415m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human EMILIN-1
    Cat.:
    P0415Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human EMILIN-1
    Cat.:
    P0415Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human EMILIN-1
    Monoclonal Antibody for Human EMILIN-1
    Protein for Human EMILIN-1
    Protein for Human EMILIN-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "EMILIN, a component of the elastic fiber and a new member of the C1q/tumor necrosis factor superfamily of proteins."
      Doliana R. , Mongiat M. , Bucciotti F. , Giacomello E. , Deutzmann R. , Volpin D. , Bressan G.M. , Colombatti A.
      J. Biol. Chem.274:16773-16781(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ARG-149
    2. 2.
      "Structure, chromosomal localization, and promoter analysis of the human elastin microfibril interface located protein (EMILIN) gene."
      Doliana R. , Canton A. , Bucciotti F. , Mongiat M. , Bonaldo P. , Colombatti A.
      J. Biol. Chem.275:785-792(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ARG-149
    3. 3.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ARG-149
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ARG-149
      tissue: Brain.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 27-1016 (ISOFORM 1);VARIANT ARG-149
      tissue: Uterus.
    7. 7.
      "Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily."
      Doliana R. , Bot S. , Mungiguerra G. , Canton A. , Cilli S.P. , Colombatti A.
      J. Biol. Chem.276:12003-12011(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    8. 8.
      "Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."
      Lewandrowski U. , Moebius J. , Walter U. , Sickmann A.
      Mol. Cell. Proteomics5:226-233(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-455
      tissue: Platelet.
    9. 9.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-415; ASN-455; ASN-766 AND ASN-794
      tissue: Liver.
    10. 10.
      "NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1."
      Verdone G. , Corazza A. , Colebrooke S.A. , Cicero D. , Eliseo T. , Boyd J. , Doliana R. , Fogolari F. , Viglino P. , Colombatti A. , Campbell I.D. , Esposito G.
      J. Biomol. NMR43:79-96(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 867-1016;SUBUNIT
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