Protein name:
EMILIN-1 ;
Alternative:
Elastin microfibril interface-located protein 1 (Elastin microfibril interfacer 1) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homotrimer associated through a moderately stable interaction of the C-terminal globular C1q domains, allowing the nucleation of the triple helix and then a further quaternary assembly to higher order polymers via intermolecular disulfide bonds. Interacts with EMILIN2.
Function:
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity (By similarity). May have a function in placenta formation and initial organogenesis and a later role in interstitial connective tissue.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Found mainly at the interface between amorphous elastin and microfibrils.
Protein Attributes:
50:
MAPRALWSCY | LCCLLTIATE | AASYPPRGYS | LYTGGTGALS | PGGPQAQNSP |
100:
RPASRHRNWC | AYVVTRTVSC | VLEDGVETIV | KPDYQPCGWG | QPHCSRSIMY |
150:
RSFLRPRYRV | AYKTVTDMEW | RCCQGYGGDD | CGEGPASVLG | PAPSTPLPRP |
200:
RPVRPNLSGS | SAGSHLSGLG | GEGPVESEKV | QQLERQVKSL | TKELQGLRGV |
250:
LQGMNGRLAE | DVQRAVDTVF | NGRQQPADAA | ARPGVHETLS | EIQQQLQLLD |
300:
NRVSTHDQEL | GHLNNHHNGG | PGGGGRASGP | VPVPSGPSEE | LLRQLERQLQ |
350:
ESCSVCLTGL | DGFRQQQQED | RERLRTLEKL | MSSMEERQQQ | LVGPAMARRP |
400:
PQECCPPELG | RRVSELERRL | DVVTGSLTVL | SGRRGSELGG | AAGQGGHPPG |
450:
YTSLASRLSR | LEDRFNSTLG | PSEEQEKNWP | GGPGRLGHWL | PAAPGRLEKL |
500:
EGLLANVSRE | LGGRMDLLEE | QVAGAVRTCG | QICSGAPGEQ | DSRVNEILSA |
550:
LERRVLDSEG | RLQLVGSGLH | EAEAAGEAQQ | AVLEGLQGLL | SRLRERMDAQ |
600:
EETAAEILLR | LNLTAAQLSQ | LEGLLQARGD | EGCGACGGVQ | EELGRLRDGV |
650:
ERCSCPLLPP | RGPGAGPGVG | GPSRGPLDGF | SVFGGSSGSA | LQALQGELSE |
700:
VILTFSSLND | SLHELQTTVE | GQGADLADLG | ATKDSIISEI | NRLQQEATEH |
750:
VTESEERFRG | LEEGQAQAGQ | CPSLEGRLGR | LEGVCERLDT | VAGGLQGLRE |
800:
GLSRHVAGLW | AAVRESNSTS | LTQAALLEKL | LGGQAGLGRR | LGALNNSLLL |
850:
LEDRLQQLSL | KDFTGPSGKA | GPPGPPGLQG | PSGPAGPPGP | PGKDGQQGAI |
900:
GPPGPQGEQG | AEGAPAAPVP | RVAFSAALSL | PRSEPGTVPF | DRVLLNDGGY |
950:
YDPETGVFTA | PLAGRYLLSA | VLTGHRHEKV | EAVLSRSNLG | VARIDSGGYE |
1000:
PEGLENKPVA | ESQPSPGALG | VFSLILPLQV | GDTVCIDLVM | GQLAHSEEPL |
1017:
TIFSGALLYE | DTELEQV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse EMILIN-1
ELISA Kit for Mouse EMILIN-1
CLIA Kit for Mouse EMILIN-1
CLIA Kit for Mouse EMILIN-1
Polyclonal Antibody for Mouse EMILIN-1
Polyclonal Antibody for Mouse EMILIN-1
Monoclonal Antibody for Mouse EMILIN-1
Monoclonal Antibody for Mouse EMILIN-1
Protein for Mouse EMILIN-1
Protein for Mouse EMILIN-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Head .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DEVELOPMENTAL STAGE