Protein name:
HERV-K_7p22.1 provirus ancestral Env polyprotein;
Alternative:
Envelope polyprotein;EnvK2 protein;HERV-K(HML-2.HOM) envelope protein;HERV-K(C7) envelope protein;HERV-K108 envelope protein;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
The surface (SU) and transmembrane (TM) proteins form a heterodimer. SU and TM are attached by noncovalent interactions or by a labile interchain disulfide bond.
Function:
TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
Subcellular Location:
HERV-K_7p22.1 provirus ancestral Env polyprotein
Virion
Protein Attributes:
50:
MNPSEMQRKA | PPRRRRHRNR | APLTHKMNKM | VTSEEQMKLP | STKKAEPPTW |
100:
AQLKKLTQLA | TKYLENTKVT | QTPESMLLAA | LMIVSMVVSL | PMPAGAAAAN |
150:
YTYWAYVPFP | PLIRAVTWMD | NPTEVYVNDS | VWVPGPIDDR | CPAKPEEEGM |
200:
MINISIGYHY | PPICLGRAPG | CLMPAVQNWL | VEVPTVSPIC | RFTYHMVSGM |
250:
SLRPRVNYLQ | DFSYQRSLKF | RPKGKPCPKE | IPKESKNTEV | LVWEECVANS |
300:
AVILQNNEFG | TIIDWAPRGQ | FYHNCSGQTQ | SCPSAQVSPA | VDSDLTESLD |
350:
KHKHKKLQSF | YPWEWGEKGI | STPRPKIVSP | VSGPEHPELW | RLTVASHHIR |
400:
IWSGNQTLET | RDRKPFYTID | LNSSLTVPLQ | SCVKPPYMLV | VGNIVIKPDS |
450:
QTITCENCRL | LTCIDSTFNW | QHRILLVRAR | EGVWIPVSMD | RPWEASPSVH |
500:
ILTEVLKGVL | NRSKRFIFTL | IAVIMGLIAV | TATAAVAGVA | LHSSVQSVNF |
550:
VNDWQKNSTR | LWNSQSSIDQ | KLANQINDLR | QTVIWMGDRL | MSLEHRFQLQ |
600:
CDWNTSDFCI | TPQIYNESEH | HWDMVRRHLQ | GREDNLTLDI | SKLKEQIFEA |
650:
SKAHLNLVPG | TEAIAGVADG | LANLNPVTWV | KTIGSTTIIN | LILILVCLFC |
699:
LLLVCRCTQQ | LRRDSDHRER | AMMTMAVLSK | RKGGNVGKSK | RDQIVTVSV
Vaild Sequence:
Related Databases
Uniprot:
