Protein name:
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7;NPP-7) ;
Alternative:
Intestinal alkaline sphingomyelinase (Alk-SMase) ;Alkaline sphingomyelin phosphodiesterase ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Localized at the surface of the microvillar membrane in small intestine enterocytes, and in endosome-like structures situated beneath the microvillar membrane, and in Golgi complex.
Protein Attributes:
50:
MGHSAVLLSV | ALVILPACVT | GGPVQRQQQH | KLLLVSFDGF | RWNYDQDVET |
100:
PNLDSMAQEG | VKARYMTPAF | VTMTSPCHFT | LVTGKYIENH | GVVHNMFYNT |
150:
TNKVRLPYHA | TLGIQRWWDN | GSIPIWITAQ | RQGLKTGSFF | YPGGNVTYQG |
200:
EAVTMSRKEG | VLHNYKNETE | WRANVDTVMK | WFTEEDVSLV | TLYFGEPDST |
250:
GHKYGPESQE | RKDMVKQVDR | TVGYLRDSIK | RHHLTDSLNL | IITSDHGMTT |
300:
VNKKASDLVE | FHKFPNFTFR | DIEFELLDYG | PNGMLIPKEG | MLEKVYSVLK |
350:
DAHPRLHVYK | KEDFPKTFHY | ANNPRITSLL | MYSDLGYVIH | GRVNVQFNSG |
400:
EHGFDNQDMD | MKTIFRAVGP | SFKAGLEVEP | FESVHVYELM | CQLLGIVPEP |
439:
NDGHPGVLQP | MLRSGSPLSR | QHHLVVVLMG | ILTGLAKVV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
ELISA Kit for Rat E-NPP 7
ELISA Kit for Rat E-NPP 7
Polyclonal Antibody for Rat E-NPP 7
Polyclonal Antibody for Rat E-NPP 7
Monoclonal Antibody for Rat E-NPP 7
Monoclonal Antibody for Rat E-NPP 7
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 32-40; 106-116; 204-211; 221-226; 255-263 AND 317-342;BIOPHYSICOCHEMICAL PROPERTIES;TISSUE SPECIFICITY
strain :
Sprague-Dawley .
tissue :
Intestinal mucosa .