ENTPD4 ELISA Kit for Human(Homo sapiens) | EIAab.comENTPD4 ELISA Kit for Human(Homo sapiens) | EIAab.com

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ENTPD4 (Gene name),

Ectonucleoside triphosphate diphosphohydrolase 4 (Protein name ), ENTP4_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

ENTPD4(KIAA0392;LALP70;LYSAL1);

Protein name:

Ectonucleoside triphosphate diphosphohydrolase 4(NTPDase 4);

Alternative:

Uridine-diphosphatase(UDPase);Lysosomal apyrase-like protein of 70 kDa;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP, AMP, ADP, ATP and UMP are not substrates. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP.

Subcellular Location:

Golgi apparatus membrane Multi-pass membrane protein Cytoplasmic vesicle autophagosome membrane Multi-pass membrane protein Localizes in the Golgi and autophagic vacuoles/lysosomes.

Protein Attributes:

Sequence length:

616

Sequence:

50:

MGRIGISCLF | PASWHFSISP | VGCPRILNTN | LRQIMVISVL | AAAVSLLYFS |

100:

VVIIRNKYGR | LTRDKKFQRY | LARVTDIEAT | DTNNPNVNYG | IVVDCGSSGS |

150:

RVFVYCWPRH | NGNPHDLLDI | RQMRDKNRKP | VVMKIKPGIS | EFATSPEKVS |

200:

DYISPLLNFA | AEHVPRAKHK | ETPLYILCTA | GMRILPESQQ | KAILEDLLTD |

250:

IPVHFDFLFS | DSHAEVISGK | QEGVYAWIGI | NFVLGRFEHI | EDDDEAVVEV |

300:

NIPGSESSEA | IVRKRTAGIL | DMGGVSTQIA | YEVPKTVSFA | SSQQEEVAKN |

350:

LLAEFNLGCD | VHQTEHVYRV | YVATFLGFGG | NAARQRYEDR | IFANTIQKNR |

400:

LLGKQTGLTP | DMPYLDPCLP | LDIKDEIQQN | GQTIYLRGTG | DFDLCRETIQ |

450:

PFMNKTNETQ | TSLNGVYQPP | IHFQNSEFYG | FSEFYYCTED | VLRMGGDYNA |

500:

AKFTKAAKDY | CATKWSILRE | RFDRGLYASH | ADLHRLKYQC | FKSAWMFEVF |

550:

HRGFSFPVNY | KSLKTALQVY | DKEVQWTLGA | ILYRTRFLPL | RDIQQEAFRA |

600:

SHTHWRGVSF | VYNHYLFSGC | FLVVLLAILL | YLLRLRRIHR | RTPRSSSAAA |

616:

LWMEEGLPAQ | NAPGTL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

MIM:

UniGene:

Pfam:

KEGG:

SMR:

STRING:

9606.ENSP00000351520

Uniprot:

FOR

ELISA Kit for Human NTPDase 4

ELISA Kit for Human NTPDase 4

CLIA Kit for Human NTPDase 4

CLIA Kit for Human NTPDase 4

Polyclonal Antibody for Human NTPDase 4

Polyclonal Antibody for Human NTPDase 4

Monoclonal Antibody for Human NTPDase 4

Monoclonal Antibody for Human NTPDase 4

Protein for Human NTPDase 4

Protein for Human NTPDase 4

R&D Technical Data

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Precision

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Recovery

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Linearity

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References

1.

"Golgi localization and functional expression of human uridine diphosphatase."
Wang T.-F. , Guidotti G.
J. Biol. Chem.273:11392-11399(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);CATALYTIC ACTIVITY;COFACTOR;CHARACTERIZATION
tissue: Brain.
2.

"A human intracellular apyrase-like protein, LALP70, localizes to lysosomal/autophagic vacuoles."
Biederbick A. , Rose S. , Elsaesser H.-P.
J. Cell Sci.112:2473-2484(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Pancreatic adenocarcinoma.
3.

"First apyrase splice variants have different enzymatic properties."
Biederbick A. , Kosan C. , Kunz J. , Elsaesser H.-P.
J. Biol. Chem.275:19018-19024(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);ALTERNATIVE SPLICING
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
Nagase T. , Ishikawa K. , Nakajima D. , Ohira M. , Seki N. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
DNA Res.4:141-150(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 59-616 (ISOFORM 2)
tissue: Brain.
6.

"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
Rush J. , Moritz A. , Lee K.A. , Guo A. , Goss V.L. , Spek E.J. , Zhang H. , Zha X.-M. , Polakiewicz R.D. , Comb M.J.
Nat. Biotechnol.23:94-101(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
7.

"Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma."
Varela I. , Tarpey P. , Raine K. , Huang D. , Ong C.K. , Stephens P. , Davies H. , Jones D. , Lin M.L. , Teague J. , Bignell G. , Butler A. , Cho J. , Dalgliesh G.L. , Galappaththige D. , Greenman C. , Hardy C. , Jia M. , more...
Nature469:539-542(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT VAL-341

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