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Index > Protein center > ENY2(Gene name) > Human
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  • ENY2 (Gene name),
  • Enhancer of yellow 2 transcription factor homolog (Protein name ),  ENY2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ENY2(DC6);
    Protein name:
    Enhancer of yellow 2 transcription factor homolog;
    Alternative:
    Enhancer of yellow 2 transcription factor homolog;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ATXN7L3, ENY2 and USP22 form a subcomplex required for histone deubiquitinylation. Interacts directly with ATXN7L3.
    Function:
    Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    101
    Sequence:
    50:
    MVVSKMNKDA | QMRAAINQKL | IETGERERLK | ELLRAKLIEC | GWKDQLKAHC | 
    100:
    KEVIKEKGLE | HVTVDDLVAE | ITPKGRALVP | DSVKKELLQR | IRTFLAQHAS | 
    101:
    L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Enhancer of yellow 2 transcription factor homolog
    ELISA Kit for Human Enhancer of yellow 2 transcription factor homolog
    ELISA Kit for Human Enhancer of yellow 2 transcription factor homolog
    CLIA Kit for Human Enhancer of yellow 2 transcription factor homolog
    CLIA Kit for Human Enhancer of yellow 2 transcription factor homolog
    CLIA Kit for Human Enhancer of yellow 2 transcription factor homolog
    Polyclonal Antibody for Human Enhancer of yellow 2 transcription factor homolog
    Polyclonal Antibody for Human Enhancer of yellow 2 transcription factor homolog
    Polyclonal Antibody for Human Enhancer of yellow 2 transcription factor homolog
    Monoclonal Antibody for Human Enhancer of yellow 2 transcription factor homolog
    Monoclonal Antibody for Human Enhancer of yellow 2 transcription factor homolog
    Monoclonal Antibody for Human Enhancer of yellow 2 transcription factor homolog
    Protein for Human Enhancer of yellow 2 transcription factor homolog
    Protein for Human Enhancer of yellow 2 transcription factor homolog
    Protein for Human Enhancer of yellow 2 transcription factor homolog

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    References
    1. 1.
      "The novel transcription factor e(y)2 interacts with TAF(II)40 and potentiates transcription activation on chromatin templates."
      Georgieva S. , Nabirochkina E. , Dilworth F.J. , Eickhoff H. , Becker P. , Tora L. , Georgiev P. , Soldatov A.
      Mol. Cell. Biol.21:5223-5231(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Novel genes expressed in human dendritic cell."
      Gu J. , Huang Q. , Yu Y. , Xu S. , Han Z. , Fu G. , Chen Z.
      Submitted (1999-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Dendritic cell.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Hippocampus.
    4. 4.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Uterus.
    7. 8.
      "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing."
      Zhao Y. , Lang G. , Ito S. , Bonnet J. , Metzger E. , Sawatsubashi S. , Suzuki E. , Le Guezennec X. , Stunnenberg H.G. , Krasnov A. , Georgieva S.G. , Schuele R. , Takeyama K. , Kato S. , Tora L. , Devys D.
      Mol. Cell29:92-101(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE SAGA COMPLEX
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 10.
      "The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements."
      Lang G. , Bonnet J. , Umlauf D. , Karmodiya K. , Koffler J. , Stierle M. , Devys D. , Tora L.
      Mol. Cell. Biol.31:3734-3744(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE SAGA COMPLEX
    10. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 12.
      "Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export."
      Jani D. , Lutz S. , Hurt E. , Laskey R.A. , Stewart M. , Wickramasinghe V.O.
      Nucleic Acids Res.40:4562-4573(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH GANP;IDENTIFICATION IN THE TREX-2 COMPLEX;SUBCELLULAR LOCATION
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