Epithelial cell adhesion molecule (Protein name
), EPCAM_PIG from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Gene name:
TACSTD1(EPCAM);
Protein name:
Epithelial cell adhesion molecule(Ep-CAM);
Alternative:
Tumor-associated calcium signal transducer 1;
CD:
CD326;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Monomer. Interacts with phosphorylated CLDN7.
Function:
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Subcellular Location:
Lateral cell membrane
Single-pass type I membrane protein
Cell junction
tight junction
Co-localizes with CLDN7 at the lateral cell membrane and tight junction.
Vaild Sequence:
