Protein name:
Ephrin type-B receptor 3 ;
Alternative:
EPH-like kinase 10 (EK10;cEK10) ;
Organism:
Chicken (Gallus gallus).
General Annotation
Sub Unit:
Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses.
Function:
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development. Beside its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. May control other aspects of development through regulation of cell migration and positioning.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Cell projection
dendrite
Protein Attributes:
50:
GVSSRARRPP | GSSRSSRRGV | TSELAWTTHP | ETGWEEVSGY | DEAMNPIRTY |
100:
QVCNVREANQ | NNWLRTKFIQ | RQDVQRVYVE | LKFTVRDCNS | IPNIPGSCKE |
150:
TFNLFYYESD | TDSASANSPF | WMENPYIKVD | TIAPDESFSK | LESGRVNTKV |
200:
RSFGPLSKNG | FYLAFQDLGA | CMSLISVRAF | YKKCSNTIAG | FAIFPETLTG |
250:
AEPTSLVIAP | GTCIPNAVEV | SVPLKLYCNG | DGEWMVPVGA | CTCAAGYEPA |
300:
MKDTQCQACG | PGTFKSKQGE | GPCSPCPPNS | RTTAGAATVC | ICRSGFFRAD |
350:
ADPADSACTS | VPSAPRSVIS | NVNETSLVLE | WSEPQDAGGR | DDLLYNVICK |
400:
KCSVERRLCS | RCDDNVEFVP | RQLGLTGLTE | RRIYISKVMA | HPQYTFEIQA |
450:
VNGISSKSPY | PPHFASVNIT | TNQAAPSAVP | TMHLHSSTGN | SMTLSWTPPE |
500:
RPNGIILDYE | IKYSEKQGQG | DGIANTVTSQ | KNSVRLDGLK | ANARYMVQVR |
550:
ARTVAGYGRY | SLPTEFQTTA | EDGSTSKTFQ | ELPLIVGSAT | AGLLFVIVVV |
600:
IIAIVCFRKG | MVTEQLLSSP | LGRKQRNSTD | PEYTEKLQQY | VTPGMKVYID |
650:
PFTYEDPNEA | VREFAKEIDI | SCVKIEEVIG | AGEFGEVCRG | RLKLPGRREI |
700:
FVAIKTLKVG | YTERQRRDFL | SEASIMGQFD | HPNIIHLEGV | VTKSRPVMII |
750:
TEFMENCALD | SFLRLNDGQF | TVIQLVGMLR | GIAAGMKYLS | EMNYVHRDLA |
800:
ARNILVNSNL | VCKVSDFGLS | RFLEDDPADP | TYTSSLGGKI | PIRWTAPEAI |
850:
AYRKFTSASD | VWSYGIVMWE | VMSYGERPYW | DMSNQDVINA | VEQDYRLPPP |
900:
MDCPTALHQL | MLDCWVRDRN | LRPKFAQIVN | TLDKLIRNAA | SLKVIASVQS |
950:
GVSQPLLDRT | VPDYTTFTTV | GDWLDAIKMG | RYKENFVNAG | FASFDLVAQM |
988:
TAEDLLRIGV | TLAGHQKKIL | SSIQDMRLQM | NQTLPVQV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Chicken
Human
ELISA Kit for Chicken Ephrin type-B receptor 3
ELISA Kit for Chicken Ephrin type-B receptor 3
ELISA Kit for Chicken Ephrin type-B receptor 3
CLIA Kit for Chicken Ephrin type-B receptor 3
CLIA Kit for Chicken Ephrin type-B receptor 3
CLIA Kit for Chicken Ephrin type-B receptor 3
Polyclonal Antibody for Chicken Ephrin type-B receptor 3
Polyclonal Antibody for Chicken Ephrin type-B receptor 3
Polyclonal Antibody for Chicken Ephrin type-B receptor 3
Monoclonal Antibody for Chicken Ephrin type-B receptor 3
Monoclonal Antibody for Chicken Ephrin type-B receptor 3
Monoclonal Antibody for Chicken Ephrin type-B receptor 3
Protein for Chicken Ephrin type-B receptor 3
Protein for Chicken Ephrin type-B receptor 3
Protein for Chicken Ephrin type-B receptor 3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS LONG AND SHORT)
tissue :
Embryo .