Epn1 ELISA Kit for Mouse(Mus musculus) | EIAab.comEpn1 ELISA Kit for Mouse(Mus musculus)

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Epn1 (Gene name),

Epsin-1 (Protein name ), EPN1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Epn1;

Protein name:

Epsin-1;

Alternative:

Intersectin-EH-binding protein 1(Ibp1);EPS-15-interacting protein 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Monomer. Binds clathrin, ZBTB16/ZNF145, ITSN1, REPS2, EPS15, AP2A1 and AP2A2. Binds ubiquitinated proteins. Interacts with RALBP1 in a complex also containing NUMB and TFAP2A during interphase and mitosis. Interacts with AP2B1.

Function:

Binds to membranes enriched in phosphatidylinositol-4,5-biphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis.

Subcellular Location:

Cytoplasm Cell membrane Peripheral membrane protein Nucleus Membrane clathrin-coated pit Associated with the cytoplasmic membrane at sites where clathrin-coated pits are forming. Colocalizes with clathrin and AP-2 in a punctate pattern on the plasma membrane. Detected in presynaptic nerve terminals and in Golgi stacks. May shuttle to the nucleus when associated with ZBTB16/ZNF145.

Protein Attributes:

Sequence length:

575

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

575:

LGGGPGLPPM | MPPGPPAPNT | NPFLL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:13854

Pfam:

PF01417

UniGene:

Mm.3091

String:

Q80VP1

SMR:

Q80VP1

Uniprot:

Q80VP1

FOR

ELISA Kit for Mouse Epsin-1

CLIA Kit for Mouse Epsin-1

Polyclonal Antibody for Mouse Epsin-1

Monoclonal Antibody for Mouse Epsin-1

Protein for Mouse Epsin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain: FVB/N.
tissue: Colon.
tissue: Limb.
tissue: Olfactory epithelium.
2.

"Intersectin, a novel adaptor protein with two eps15 homology and five src homology 3 domains."
Yamabhai M. , Hoffman N.G. , Hardison N.L. , McPherson P.S. , Castagnoli L. , Cesareni G. , Kay B.K.
J. Biol. Chem.273:31401-31407(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 365-575 (ISOFORM 2);INTERACTION WITH ITSN1
tissue: Embryo.
3.

"The interaction of epsin and Eps15 with the clathrin adaptor AP-2 is inhibited by mitotic phosphorylation and enhanced by stimulation-dependent dephosphorylation in nerve terminals."
Chen H. , Slepnev V.I. , Di Fiore P.P. , De Camilli P.
J. Biol. Chem.274:3257-3260(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;INTERACTION WITH AP2A1 AND AP2A2
4.

"Phosphoproteomic analysis of the developing mouse brain."
Ballif B.A. , Villen J. , Beausoleil S.A. , Schwartz D. , Gygi S.P.
Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic brain.
5.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
6.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-469;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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