ERCC6L ELISA Kit for Bovine(Bos taurus) | EIAab.comERCC6L ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > ERCC6L(Gene name) > Bovine

ERCC6L (Gene name),

DNA excision repair protein ERCC-6-like (Protein name ), ERC6L_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ERCC6L;

Protein name:

DNA excision repair protein ERCC-6-like;

Alternative:

ATP-dependent helicase ERCC6-like;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Interacts with PLK1, which phosphorylates it. Both proteins are mutually dependent on each other for correct subcellular localization.

Function:

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

Subcellular Location:

Chromosome centromere Chromosome centromere kinetochore Localizes to kinetochores, inner centromeres and thin threads connecting separating chromosomes even during anaphase. In prometaphase cells, it mostly concentrates in between kinetochores. In metaphase, it localizes to numerous thin threads that stretch between sister kinetochores of the aligned chromosomes and are composed of catenated centromeric DNA. Evolution from inner centromeres to thin threads takes place in response to tension. Resolution of thin threads requires topoisomerase 2-alpha (TOP2A) after anaphase onset.

Protein Attributes:

Sequence length:

1242

Sequence:

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1242:

ELKECGKIQE | ALDCLVKALD | IKSSDPEVML | MTLSLYKQLN | KT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Bt.74729

KEGG:

bta:782916

STRING:

9913.ENSBTAP00000007362

String:

A6QQR4

Pfam:

PF00271

Uniprot:

A6QQR4

FOR

ELISA Kit for Bovine DNA excision repair protein ERCC-6-like

CLIA Kit for Bovine DNA excision repair protein ERCC-6-like

Polyclonal Antibody for Bovine DNA excision repair protein ERCC-6-like

Monoclonal Antibody for Bovine DNA excision repair protein ERCC-6-like

Protein for Bovine DNA excision repair protein ERCC-6-like

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2007-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Thymus.
2.

"Characterization of 954 bovine full-CDS cDNA sequences."
Harhay G.P. , Sonstegard T.S. , Keele J.W. , Heaton M.P. , Clawson M.L. , Snelling W.M. , Wiedmann R.T. , Van Tassell C.P. , Smith T.P.L.
BMC Genomics6:166-166(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 705-1242

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