ERCC2 ELISA Kit for Bovine(Bos taurus) | EIAab.comERCC2 ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > ERCC2(Gene name) > Bovine

ERCC2 (Gene name),

TFIIH basal transcription factor complex helicase XPD subunit (Protein name ), ERCC2_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ERCC2;

Protein name:

TFIIH basal transcription factor complex helicase XPD subunit;

Alternative:

DNA excision repair protein ERCC-2;CXPD;Xeroderma pigmentosum group D-complementing protein;DNA repair protein complementing XP-D cells;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

One of the six subunits forming the core-TFIIH basal transcription factor which associates with the CAK complex composed of CDK7, CCNH/cyclin H and MNAT1 to form the TFIIH basal transcription factor. The interaction with GTF2H2 results in the stimulation of the 5'-->3' helicase activity. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with FAM196B; the interaction is direct (By similarity). Interacts with ATF7IP.

Function:

ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.

Subcellular Location:

Nucleus Cytoplasm cytoskeleton spindle

Protein Attributes:

Sequence length:

760

Sequence:

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760:

RRIEQIAQQL |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF06733

UniGene:

Bt.4215

KEGG:

bta:100125238

String:

A6QLJ0

Uniprot:

A6QLJ0

FOR

ELISA Kit for Bovine TFIIH basal transcription factor complex helicase XPD subunit

CLIA Kit for Bovine TFIIH basal transcription factor complex helicase XPD subunit

Polyclonal Antibody for Bovine TFIIH basal transcription factor complex helicase XPD subunit

Monoclonal Antibody for Bovine TFIIH basal transcription factor complex helicase XPD subunit

Protein for Bovine TFIIH basal transcription factor complex helicase XPD subunit

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2007-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Uterus.

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