Gene name:
Ercc3 (Xpb;Xpbc) ;
Protein name:
TFIIH basal transcription factor complex helicase XPB subunit ;
Alternative:
DNA excision repair protein ERCC-3 ;Basic transcription factor 2 89 kDa subunit (BTF2 p89) ;TFIIH 89 kDa subunit ;DNA repair protein complementing XP-B cells ;Xeroderma pigmentosum group B-complementing protein ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
One of the 6 subunits forming the core-TFIIH basal transcription factor which associates with the CAK complex composed of CDK7, CCNH/cyclin H and MNAT1 to form the TFIIH basal transcription factor. Interacts with PUF60 (By similarity). Interacts with ATF7IP.
Function:
ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MGKRDRVDRD | KKKSKKRQYE | EEEEDEDDIP | GNESQEAVPS | AAGKQVDESS |
100:
TKVDEYGAKD | YRQQMPLKGD | HTSRPLWVAP | DGHIFLEAFS | PVYKYAQDFL |
150:
VAIAEPVCRP | THVHEYKLTA | YSLYAAVSVG | LQTSDITEYL | RKLSKTGVPD |
200:
GIIQFIKLCT | VSYGKVKLVL | KHNRYFVESS | HPDVIQHLLQ | DPVIRECRLR |
250:
NAEGEATELI | TETFTSKSAI | SKTAAEGSGG | PSTSQGVDAQ | ATSDIPKDLF |
300:
DFYEQMDKDE | EEEEETQTVS | FEVKQEMIEE | LQKRCICLEY | PLLAEYDFRN |
350:
DTLNPDINID | LKPTAVLRPY | QEKSLRKMFG | NGRARSGVIV | LPCGAGKSLV |
400:
GVTAACTVRK | RCLVLGNSAV | SVEQWKAQFK | MWSTIDDSQI | CRFTSDAKDK |
450:
PIGCSVAIST | YSMLGHTTKR | SWEAERVMEW | LKTQEWGLMI | LDEVHTIPAR |
500:
MFRRVLTIVQ | AHCKLGLTAT | LVREDDKIVD | LNFLIGPKLY | EANWMELQNN |
550:
GYIAKVQCAE | VWCPMSPEFY | REYVAIKTKK | RILLYTMNPN | KFRACQFLIK |
600:
FHERRNDKII | VFADNVFALK | EYAIRLNKPY | IYGPTSQGER | MQILQNFKHN |
650:
PKINTIFISK | VGDTSFDLPE | ANVLIQISSH | GGSRRQEAQR | LGRVLRAKKG |
700:
MVAEEYNAFF | YSLVSQDTQE | MAYSTKRQRF | LVDQGYSFKV | ITKLAGMEEE |
750:
ELAFSTKEEQ | QQLLQKVLAA | TDLDAEEEVV | AGEFGSRSGQ | ASRRCGTMSS |
783:
LSGADDTVYM | EYHSSRSKAS | SKHVHPLFKR | FRK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Human
Chicken
Rat
ELISA Kit for Mouse TFIIH basal transcription factor complex helicase XPB subunit
ELISA Kit for Mouse TFIIH basal transcription factor complex helicase XPB subunit
ELISA Kit for Mouse TFIIH basal transcription factor complex helicase XPB subunit
ELISA Kit for Mouse TFIIH basal transcription factor complex helicase XPB subunit
ELISA Kit for Mouse TFIIH basal transcription factor complex helicase XPB subunit
CLIA Kit for Mouse TFIIH basal transcription factor complex helicase XPB subunit
CLIA Kit for Mouse TFIIH basal transcription factor complex helicase XPB subunit
CLIA Kit for Mouse TFIIH basal transcription factor complex helicase XPB subunit
CLIA Kit for Mouse TFIIH basal transcription factor complex helicase XPB subunit
CLIA Kit for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Polyclonal Antibody for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Polyclonal Antibody for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Polyclonal Antibody for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Polyclonal Antibody for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Polyclonal Antibody for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Monoclonal Antibody for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Monoclonal Antibody for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Monoclonal Antibody for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Monoclonal Antibody for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Monoclonal Antibody for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Protein for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Protein for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Protein for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Protein for Mouse TFIIH basal transcription factor complex helicase XPB subunit
Protein for Mouse TFIIH basal transcription factor complex helicase XPB subunit
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Mammary gland .