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Index > Protein center > ERF(Gene name) > Human
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  • ERF (Gene name),
  • ETS domain-containing transcription factor ERF (Protein name ),  ERF_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ERF;
    Protein name:
    ETS domain-containing transcription factor ERF;
    Alternative:
    PE-2;Ets2 repressor factor;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    548
    Sequence:
    50:
    MKTPADTGFA | FPDWAYKPES | SPGSRQIQLW | HFILELLRKE | EYQGVIAWQG | 
    100:
    DYGEFVIKDP | DEVARLWGVR | KCKPQMNYDK | LSRALRYYYN | KRILHKTKGK | 
    150:
    RFTYKFNFNK | LVLVNYPFID | VGLAGGAVPQ | SAPPVPSGGS | HFRFPPSTPS | 
    200:
    EVLSPTEDPR | SPPACSSSSS | SLFSAVVARR | LGRGSVSDCS | DGTSELEEPL | 
    250:
    GEDPRARPPG | PPDLGAFRGP | PLARLPHDPG | VFRVYPRPRG | GPEPLSPFPV | 
    300:
    SPLAGPGSLL | PPQLSPALPM | TPTHLAYTPS | PTLSPMYPSG | GGGPSGSGGG | 
    350:
    SHFSFSPEDM | KRYLQAHTQS | VYNYHLSPRA | FLHYPGLVVP | QPQRPDKCPL | 
    400:
    PPMAPETPPV | PSSASSSSSS | SSSPFKFKLQ | PPPLGRRQRA | AGEKAVAGAD | 
    450:
    KSGGSAGGLA | EGAGALAPPP | PPPQIKVEPI | SEGESEEVEV | TDISDEDEED | 
    500:
    GEVFKTPRAP | PAPPKPEPGE | APGASQCMPL | KLRFKRRWSE | DCRLEGGGGP | 
    548:
    AGGFEDEGED | KKVRGEGPGE | AGGPLTPRRV | SSDLQHATAQ | LSLEHRDS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    String:
    KEGG:
    MIM:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human ETS domain-containing transcription factor ERF
    ELISA Kit for Human ETS domain-containing transcription factor ERF
    CLIA Kit for Human ETS domain-containing transcription factor ERF
    CLIA Kit for Human ETS domain-containing transcription factor ERF
    Polyclonal Antibody for Human ETS domain-containing transcription factor ERF
    Polyclonal Antibody for Human ETS domain-containing transcription factor ERF
    Monoclonal Antibody for Human ETS domain-containing transcription factor ERF
    Monoclonal Antibody for Human ETS domain-containing transcription factor ERF
    Protein for Human ETS domain-containing transcription factor ERF
    Protein for Human ETS domain-containing transcription factor ERF

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation."
      Sgouras D.N. , Athanasiou M.A. , Beal G.J. Jr. , Fisher R.J. , Blair D.G. , Mavrothalassitis G.J.
      EMBO J.14:4781-4793(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PHOSPHORYLATION AT THR-526;MUTAGENESIS OF THR-526
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Heart.
    3. 3.
      Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S. , Ohara O. , Nagase T. , Kikuno R.F.
      Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    4. 4.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Duodenum.
    7. 7.
      Bienvenut W.V. , Lempens A. , Norman J.C.
      Submitted (2009-10) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 102-110; 206-218; 313-347; 377-386; 402-426 AND 515-528;PHOSPHORYLATION AT SER-327;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Ovarian carcinoma.
    8. 8.
      "Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF)."
      de Castro C.M. , Rabe S.M. , Langdon S.D. , Fleenor D.E. , Slentz-Kesler K. , Ahmed M.N. , Qumsiyeh M.B. , Kaufman R.E.
      Genomics42:227-235(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    9. 9.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-190;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-3; THR-7; SER-20; SER-185; SER-327; SER-431; SER-435; THR-441; SER-444; SER-531 AND SER-548;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-431; SER-444 AND THR-526;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    12. 12.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CRS4 GLN-65 AND CYS-86
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