ERG ELISA Kit for Human(Homo sapiens) | EIAab.comERG ELISA Kit for Human(Homo sapiens) | EIAab.com

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ERG (Gene name),

Transcriptional regulator ERG (Protein name ), ERG_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

ERG;

Protein name:

Transcriptional regulator ERG;

Alternative:

Transforming protein ERG;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with SETDB1 (By similarity). Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs.

Function:

Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.

Subcellular Location:

Nucleus Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Protein Attributes:

Sequence length:

486

Sequence:

50:

MIQTVPDPAA | HIKEALSVVS | EDQSLFECAY | GTPHLAKTEM | TASSSSDYGQ |

100:

TSKMSPRVPQ | QDWLSQPPAR | VTIKMECNPS | QVNGSRNSPD | ECSVAKGGKM |

150:

VGSPDTVGMN | YGSYMEEKHM | PPPNMTTNER | RVIVPADPTL | WSTDHVRQWL |

200:

EWAVKEYGLP | DVNILLFQNI | DGKELCKMTK | DDFQRLTPSY | NADILLSHLH |

250:

YLRETPLPHL | TSDDVDKALQ | NSPRLMHARN | TGGAAFIFPN | TSVYPEATQR |

300:

ITTRPDLPYE | PPRRSAWTGH | GHPTPQSKAA | QPSPSTVPKT | EDQRPQLDPY |

350:

QILGPTSSRL | ANPGSGQIQL | WQFLLELLSD | SSNSSCITWE | GTNGEFKMTD |

400:

PDEVARRWGE | RKSKPNMNYD | KLSRALRYYY | DKNIMTKVHG | KRYAYKFDFH |

450:

GIAQALQPHP | PESSLYKYPS | DLPYMGSYHA | HPQKMNFVAP | HPPALPVTSS |

486:

SFFAAPNPYW | NSPTGGIYPN | TRLPTSHMPS | HLGTYY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

MIM:

String:

KEGG:

UniGene:

Pfam:

STRING:

9606.ENSP00000381891

Uniprot:

FOR

ELISA Kit for Human Transcriptional regulator ERG

ELISA Kit for Human Transcriptional regulator ERG

ELISA Kit for Human Transcriptional regulator ERG

CLIA Kit for Human Transcriptional regulator ERG

CLIA Kit for Human Transcriptional regulator ERG

CLIA Kit for Human Transcriptional regulator ERG

Polyclonal Antibody for Human Transcriptional regulator ERG

Polyclonal Antibody for Human Transcriptional regulator ERG

Polyclonal Antibody for Human Transcriptional regulator ERG

Monoclonal Antibody for Human Transcriptional regulator ERG

Monoclonal Antibody for Human Transcriptional regulator ERG

Monoclonal Antibody for Human Transcriptional regulator ERG

Protein for Human Transcriptional regulator ERG

Protein for Human Transcriptional regulator ERG

Protein for Human Transcriptional regulator ERG

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"erg, a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation."
Rao V.N. , Papas T.S. , Shyam E. , Reddy P.
Science237:635-639(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ERG-2)
2.

"The erg gene: a human gene related to the ets oncogene."
Reddy E.S.P. , Rao V.N. , Papas T.S.
Proc. Natl. Acad. Sci. U.S.A.84:6131-6135(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ERG-1)
3.

"Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16."
Owczarek C.M. , Portbury K.J. , Hardy M.P. , O'Leary D.A. , Kudoh J. , Shibuya K. , Shimizu N. , Kola I. , Hertzog P.J.
Gene324:65-77(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 7)
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 5 AND ERG-1)
tissue: Thymus.
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5)
tissue: Testis.
6.

"Differentially spliced erg-3 product functions as a transcriptional activator."
Prasad D.D. , Rao V.N. , Lee L. , Reddy E.S.
Oncogene9:669-673(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 230-259 (ISOFORM ERG-3)
7.

"ERG gene is translocated in an Ewing's sarcoma cell line."
Dunn T. , Praissman L. , Hagag N. , Viola M.V.
Cancer Genet. Cytogenet.76:19-22(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH EWSR1
8.

"An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation."
Ichikawa H. , Shimizu K. , Hayashi Y. , Ohki M.
Cancer Res.54:2865-2868(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH FUS
9.

"ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21)(q25-26;q22)."
Moore S.D. , Offor O. , Ferry J.A. , Amrein P.C. , Morton C.C. , Dal Cin P.
Leuk. Res.30:1037-1042(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH ELF4
10.

"Molecular composition of IMP1 ribonucleoprotein granules."
Joeson L. , Vikesaa J. , Krogh A. , Nielsen L.K. , Hansen T. , Borup R. , Johnsen A.H. , Christiansen J. , Nielsen F.C.
Mol. Cell. Proteomics6:798-811(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A MRNP GRANULE COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY;SUBCELLULAR LOCATION
11.

"Diversity in structure and function of the Ets family PNT domains."
Mackereth C.D. , Scharpf M. , Gentile L.N. , MacIntosh S.E. , Slupsky C.M. , McIntosh L.P.
J. Mol. Biol.342:1249-1264(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 112-208

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