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Index > Protein center > ERO1L(Gene name) > Pig
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  • ERO1L (Gene name),
  • ERO1-like protein alpha (Protein name ),  ERO1A_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ERO1L;
    Protein name:
    ERO1-like protein alpha(ERO1-L;ERO1-L-alpha);
    Alternative:
    Oxidoreductin-1-L-alpha;Endoplasmic oxidoreductin-1-like protein;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Predominantly monomer. May function both as a monomer and a homodimer. Interacts with PDILT.
    Function:
    Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress. Required for the folding of immunoglobulin proteins.
    Subcellular Location:
    Endoplasmic reticulum membrane Peripheral membrane protein Lumenal side The association with ERP44 is essential for its retention in the endoplasmic reticulum.
    Protein Attributes:
    Sequence length:
    468
    Sequence:
    50:
    MGHRWGFLIV | FLGAVGLLGS | GYGRQQPSET | AAQRCFCQVS | GYLDDCTCDV | 
    100:
    ETIDRFNNYR | LFPRLQKLLE | SDYFRYYKVN | LKRPCPFWND | INQCGRRDCA | 
    150:
    VKPCQSDEIP | DGIKSASYKY | SEEANNLIEE | CEQAERLGAV | DESLSEETQK | 
    200:
    AVLQWTKHDD | SSDNFCEADD | IQSPDAEYVD | LLLNPERYTG | YKGPDAWKIW | 
    250:
    NVIYEENCFK | PQTIKRPLNP | LASGQGKSEE | NTFYSWLEGL | CVEKRAFYRL | 
    300:
    ISGLHASINV | HLSARYLLQD | TWLEKKWGHN | ITEFQQRFDG | ILTEGEGPRR | 
    350:
    LKNLYFLYLI | ELRALSKVVP | FFERPDFQLF | TGNKVQDAEN | KMLLLDILHE | 
    400:
    IKSFPLHFDE | NSFFAGDKKE | ANKLKEDFRL | HFRNISRIMD | CVGCLKCRLW | 
    450:
    GKLQTQGLGT | ALKILFSEKL | IANMPESGPS | YEFHLTRQEI | VSLFNAFGRI | 
    468:
    STSVKELENF | RNLLQNIH
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Pig ERO1-L
    ELISA Kit for Pig ERO1-L
    ELISA Kit for Pig ERO1-L
    ELISA Kit for Pig ERO1-L
    ELISA Kit for Pig ERO1-L
    CLIA Kit for Pig ERO1-L
    CLIA Kit for Pig ERO1-L
    CLIA Kit for Pig ERO1-L
    CLIA Kit for Pig ERO1-L
    CLIA Kit for Pig ERO1-L
    Polyclonal Antibody for Pig ERO1-L
    Polyclonal Antibody for Pig ERO1-L
    Polyclonal Antibody for Pig ERO1-L
    Polyclonal Antibody for Pig ERO1-L
    Polyclonal Antibody for Pig ERO1-L
    Monoclonal Antibody for Pig ERO1-L
    Monoclonal Antibody for Pig ERO1-L
    Monoclonal Antibody for Pig ERO1-L
    Monoclonal Antibody for Pig ERO1-L
    Monoclonal Antibody for Pig ERO1-L
    Protein for Pig ERO1-L
    Protein for Pig ERO1-L
    Protein for Pig ERO1-L
    Protein for Pig ERO1-L
    Protein for Pig ERO1-L

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    References
    1. 1.
      Long Q. , Yang Z.
      Submitted (2008-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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