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Index > Protein center > Erp44(Gene name) > Mouse
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  • Erp44 (Gene name),
  • Endoplasmic reticulum resident protein 44 (Protein name ),  ERP44_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Erp44(Kiaa0573;Txndc4);
    Protein name:
    Endoplasmic reticulum resident protein 44(ER protein 44;ERp44);
    Alternative:
    Thioredoxin domain-containing protein 4;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Forms mixed disulfides with both ERO1L and ERO1LB and cargo folding intermediates (By similarity). Directly interacts with ITPR1 in a pH-, redox state- and calcium-dependent manner, but not with ITPR2 or ITPR3. The strength of this interaction inversely correlates with calcium concentration.
    Function:
    Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
    Subcellular Location:
    Endoplasmic reticulum lumen
    Protein Attributes:
    Sequence length:
    406
    Sequence:
    50:
    MNPAVFLSLA | DLRCSLLLLV | TSIFTPITAE | IASLDSENID | EILNNADVAL | 
    100:
    VNFYADWCRF | SQMLHPIFEE | ASDVIKEEYP | DKNQVVFARV | DCDQHSDIAQ | 
    150:
    RYRISKYPTL | KLFRNGMMMK | REYRGQRSVK | ALADYIRQQK | SNPVHEIQSL | 
    200:
    DEVTNLDRSK | RNIIGYFEQK | DSENYRVFER | VASILHDDCA | FLSAFGDLSK | 
    250:
    PERYNGDNVI | YKPPGRSAPD | MVYLGSMTNF | DVTYNWIQDK | CVPLVREITF | 
    300:
    ENGEELTEEG | LPFLILFHMK | DDTESLEIFQ | NEVARQLISE | KGTINFLHAD | 
    350:
    CDKFRHPLLH | IQKTPADCPV | IAIDSFRHMY | VFGDFKDVLI | PGKLKQFVFD | 
    400:
    LHSGKLHREF | HHGPDPTDTA | PGEQDQDVAS | SPPESSFQKL | APSEYRYTLL | 
    406:
    RDRDEL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ER protein 44
    ELISA Kit for Mouse ER protein 44
    ELISA Kit for Mouse ER protein 44
    CLIA Kit for Mouse ER protein 44
    CLIA Kit for Mouse ER protein 44
    CLIA Kit for Mouse ER protein 44
    Polyclonal Antibody for Mouse ER protein 44
    Polyclonal Antibody for Mouse ER protein 44
    Polyclonal Antibody for Mouse ER protein 44
    Monoclonal Antibody for Mouse ER protein 44
    Monoclonal Antibody for Mouse ER protein 44
    Monoclonal Antibody for Mouse ER protein 44
    Protein for Mouse ER protein 44
    Protein for Mouse ER protein 44
    Protein for Mouse ER protein 44

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Bone marrow.
      tissue: Embryo.
    2. 2.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Seino S. , Nishimura M. , Kaisho T. , Hoshino K. , Kitamura H. , Nagase T. , Ohara O. , Koga H.
      DNA Res.11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Fetal brain.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Salivary gland.
    4. 4.
      "Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44."
      Higo T. , Hattori M. , Nakamura T. , Natsume T. , Michikawa T. , Mikoshiba K.
      Cell120:85-98(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITPR1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MUTAGENESIS OF CYS-58
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