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Index > Protein center > Esrra(Gene name) > Rat
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  • Esrra (Gene name),
  • Steroid hormone receptor ERR1 (Protein name ),  ERR1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Esrra(Nr3b1);
    Protein name:
    Steroid hormone receptor ERR1;
    Alternative:
    Nuclear receptor subfamily 3 group B member 1;Estrogen-related receptor alpha(ERR-alpha);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Binds DNA as a monomer or a homodimer. Interacts (via the AF2 domain) with coactivator PPARGC1A (via the L3 motif); the interaction greatly enhances transriptional activity of genes involved in energy metabolism. Interacts with PIAS4; the interaction enhances sumoylation.
    Function:
    Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    422
    Sequence:
    50:
    MSSQVVGIEP | LYIKAEPASP | DSPKGSSETE | TEPPVTLASG | PAPARCLPGH | 
    100:
    KEEEDGEGAG | SGEQGSGKLV | LSSLPKRLCL | VCGDVASGYH | YGVASCEACK | 
    150:
    AFFKRTIQGS | IEYSCPASNE | CEITKRRRKA | CQACRFTKCL | RVGMLKEGVR | 
    200:
    LDRVRGGRQK | YKRRPEVDPL | PFPGPFPAGP | LAVAGGPRKT | APVNALVSHL | 
    250:
    LVVEPEKLYA | MPDPASPDGH | LPAVATLCDL | FDREIVVTIS | WAKSIPGFSS | 
    300:
    LSLSDQMSVL | QSVWMEVLVL | GVAQRSLPLQ | DELAFAEDLV | LDEEGARAAG | 
    350:
    LGDLGAALLQ | LVRRLQALRL | EREEYVLLKA | LALANSDSVH | IEDAEAVEQL | 
    400:
    REALHEALLE | YEAGRAGPGG | GAERRRAGRL | LLTLPLLRQT | AGKVLAHFYG | 
    422:
    VKLEGKVPMH | KLFLEMLEAM | MD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Steroid hormone receptor ERR1
    ELISA Kit for Rat Steroid hormone receptor ERR1
    ELISA Kit for Rat Steroid hormone receptor ERR1
    ELISA Kit for Rat Steroid hormone receptor ERR1
    CLIA Kit for Rat Steroid hormone receptor ERR1
    CLIA Kit for Rat Steroid hormone receptor ERR1
    CLIA Kit for Rat Steroid hormone receptor ERR1
    CLIA Kit for Rat Steroid hormone receptor ERR1
    Polyclonal Antibody for Rat Steroid hormone receptor ERR1
    Polyclonal Antibody for Rat Steroid hormone receptor ERR1
    Polyclonal Antibody for Rat Steroid hormone receptor ERR1
    Polyclonal Antibody for Rat Steroid hormone receptor ERR1
    Monoclonal Antibody for Rat Steroid hormone receptor ERR1
    Monoclonal Antibody for Rat Steroid hormone receptor ERR1
    Monoclonal Antibody for Rat Steroid hormone receptor ERR1
    Monoclonal Antibody for Rat Steroid hormone receptor ERR1
    Protein for Rat Steroid hormone receptor ERR1
    Protein for Rat Steroid hormone receptor ERR1
    Protein for Rat Steroid hormone receptor ERR1
    Protein for Rat Steroid hormone receptor ERR1

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    References
    1. 1.
      "Molecular cloning and expression study of estrogen receptor-related receptor alpha in rat ovary."
      Lui K. , Chen S. , Chan F.L.
      Submitted (2003-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Heart.
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