Gene name:
ESRP2 (PP7059;RBM35B) ;
Protein name:
Epithelial splicing regulatory protein 2 ;
Alternative:
RNA-binding protein 35B ;RNA-binding motif protein 35B ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MTPPPPPPPP | PGPDPAADPA | ADPCPWPGSL | VVLFGATAGA | LGRDLGSDET |
100:
DLILLVWQVV | EPRSRQVGTL | HKSLVRAEAA | ALSTQCREAS | GLSADSLARA |
150:
EPLDKVLQQF | SQLVNGDVAL | LGGGPYMLCT | DGQQLLRQVL | HPEASRKNLV |
200:
LPDMFFSFYD | LRREFHMQHP | STCPARDLTV | ATMAQGLGLE | TDATEDDFGV |
250:
WEVKTMVAVI | LHLLKEPSSQ | LFSKPEVIKQ | KYETGPCSDS | TVPCPYSSKA |
300:
DVVDSETVVR | ARGLPWQSSD | QDVARFFKGL | NVARGGVALC | LNAQGRRNGE |
350:
ALIRFVDSEQ | RDLALQRHKH | HMGVRYIEVY | KATGEEFVKI | AGGTSLEVAR |
400:
FLSREDQVIL | RLRGLPFSAG | PTDVLGFLGP | ECPVTGGTEG | LLFVRHPDGR |
450:
PTGDAFALFA | CEELAQAALR | RHKGMLGKRY | IELFRSTAAE | VQQVLNRYAS |
500:
GPLLPTLTAP | LLPIPFPLAP | GTGRDCVRLR | GLPYTATIED | ILSFLGEAAA |
550:
DIRPHGVHMV | LNQQGRPSGD | AFIQMTSAER | ALAAAQRCHK | KVMKERYVEV |
600:
VPCSTEEMSR | VLMGGTLGRS | GMSPPPCKLP | CLSPPTYTTF | QATPTLIPTE |
650:
TAALYPSSAL | LPAARVPAAP | TPVAYYPGPA | TQLYLNYTAY | YPSPPVSPTT |
700:
VGYLTTPTAA | LASAPTSVLS | QSGALVRMQG | VPYTAGMKDL | LSVFQAYQLP |
727:
ADDYTSLMPV | GDPPRTVLQA | PKEWVCL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Mouse
Human
Rat
ELISA Kit for Human Epithelial splicing regulatory protein 2
ELISA Kit for Human Epithelial splicing regulatory protein 2
ELISA Kit for Human Epithelial splicing regulatory protein 2
ELISA Kit for Human Epithelial splicing regulatory protein 2
CLIA Kit for Human Epithelial splicing regulatory protein 2
CLIA Kit for Human Epithelial splicing regulatory protein 2
CLIA Kit for Human Epithelial splicing regulatory protein 2
CLIA Kit for Human Epithelial splicing regulatory protein 2
Polyclonal Antibody for Human Epithelial splicing regulatory protein 2
Polyclonal Antibody for Human Epithelial splicing regulatory protein 2
Polyclonal Antibody for Human Epithelial splicing regulatory protein 2
Polyclonal Antibody for Human Epithelial splicing regulatory protein 2
Monoclonal Antibody for Human Epithelial splicing regulatory protein 2
Monoclonal Antibody for Human Epithelial splicing regulatory protein 2
Monoclonal Antibody for Human Epithelial splicing regulatory protein 2
Monoclonal Antibody for Human Epithelial splicing regulatory protein 2
Protein for Human Epithelial splicing regulatory protein 2
Protein for Human Epithelial splicing regulatory protein 2
Protein for Human Epithelial splicing regulatory protein 2
Protein for Human Epithelial splicing regulatory protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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