Gene name:
Esrp2 (Rbm35b) ;
Protein name:
Epithelial splicing regulatory protein 2 ;
Alternative:
RNA-binding protein 35B ;RNA-binding motif protein 35B ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MTPPPPPPPP | PGPDPAVDSS | TDPCPEPQSL | VVLFGATAGA | LGPDLGSDET |
100:
DLILLVWQVV | EPRSRQVGTL | HKSLVRAEAA | ALSPQCREAS | GLSADSLARA |
150:
ESLDKVLQQF | SQLVSGDVAL | LGGGPYVLCT | DGQQLLRQVL | HPEASRKNLV |
200:
LPDTFFSFYD | LRREFHVQHP | STCSARDLTV | GTMAQDLGLE | TDATEDDFGV |
250:
WEVKTMVAVI | LHLLEGPNGH | LFSKPEVVKQ | KYETGPCKAD | VVDNETVVRA |
300:
RGLPWQSSDQ | DVARFFKGLN | IARGGVALCL | NAQGRRNGEA | LIRFEDSEQR |
350:
DLALQRHKHH | MGVRYIEVYK | ATGEEFVKIA | GGTSLEVARF | LSREDQVILR |
400:
LRGLPFSAGP | ADVLDFLGPE | CPVTGGVDGL | LFVRHPDGRP | TGDAFALFAC |
450:
EELAQAALRR | HKGMLGKRYI | ELFRSTAAEV | QQVLNRYAAS | PLLPTLTAPL |
500:
LPIPFPLAGG | TGRDCVRLRG | LPYTATIEDI | LSFLGEAAAD | IRPHGVHMVL |
550:
NQQGRPSGDA | FIQMMSVERA | LAAAQRCHKK | VMKERYVEVV | PCSTEEMSRV |
600:
LMGGSLSRSG | LSPPPCKLPC | LSPPTYATFQ | ASPALIPTET | TALYPSSALL |
650:
PAARVPAAAT | PLAYYPGPAT | QLYMNYTAYY | PSPPVSPTTV | GYLTTPPTAL |
700:
ASTPTSMLSQ | PGALVRMQGV | PYTAGMKDLL | SVFQAYQLAP | DDYATLVPVG |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Mouse
Human
Rat
ELISA Kit for Rat Epithelial splicing regulatory protein 2
ELISA Kit for Rat Epithelial splicing regulatory protein 2
ELISA Kit for Rat Epithelial splicing regulatory protein 2
ELISA Kit for Rat Epithelial splicing regulatory protein 2
CLIA Kit for Rat Epithelial splicing regulatory protein 2
CLIA Kit for Rat Epithelial splicing regulatory protein 2
CLIA Kit for Rat Epithelial splicing regulatory protein 2
CLIA Kit for Rat Epithelial splicing regulatory protein 2
Polyclonal Antibody for Rat Epithelial splicing regulatory protein 2
Polyclonal Antibody for Rat Epithelial splicing regulatory protein 2
Polyclonal Antibody for Rat Epithelial splicing regulatory protein 2
Polyclonal Antibody for Rat Epithelial splicing regulatory protein 2
Monoclonal Antibody for Rat Epithelial splicing regulatory protein 2
Monoclonal Antibody for Rat Epithelial splicing regulatory protein 2
Monoclonal Antibody for Rat Epithelial splicing regulatory protein 2
Monoclonal Antibody for Rat Epithelial splicing regulatory protein 2
Protein for Rat Epithelial splicing regulatory protein 2
Protein for Rat Epithelial splicing regulatory protein 2
Protein for Rat Epithelial splicing regulatory protein 2
Protein for Rat Epithelial splicing regulatory protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Prostate .