Gene name:
ESYT1 (FAM62A;KIAA0747;MBC2) ;
Protein name:
Extended synaptotagmin-1 (E-Syt1) ;
Alternative:
Membrane-bound C2 domain-containing protein ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
May play a role as calcium-regulated intrinsic membrane protein.
Subcellular Location:
Membrane
Multi-pass membrane protein
Localizes to intracellular membranes.
Protein Attributes:
50:
MERSPGEGPS | PSPMDQPSAP | SDPTDQPPAA | HAKPDPGSGG | QPAGPGAAGE |
100:
ALAVLTSFGR | RLLVLIPVYL | AGAVGLSVGF | VLFGLALYLG | WRRVRDEKER |
150:
SLRAARQLLD | DEEQLTAKTL | YMSHRELPAW | VSFPDVEKAE | WLNKIVAQVW |
200:
PFLGQYMEKL | LAETVAPAVR | GSNPHLQTFT | FTRVELGEKP | LRIIGVKVHP |
250:
GQRKEQILLD | LNISYVGDVQ | IDVEVKKYFC | KAGVKGMQLH | GVLRVILEPL |
300:
IGDLPFVGAV | SMFFIRRPTL | DINWTGMTNL | LDIPGLSSLS | DTMIMDSIAA |
350:
FLVLPNRLLV | PLVPDLQDVA | QLRSPLPRGI | IRIHLLAARG | LSSKDKYVKG |
400:
LIEGKSDPYA | LVRLGTQTFC | SRVIDEELNP | QWGETYEVMV | HEVPGQEIEV |
450:
EVFDKDPDKD | DFLGRMKLDV | GKVLQASVLD | DWFPLQGGQG | QVHLRLEWLS |
500:
LLSDAEKLEQ | VLQWNWGVSS | RPDPPSAAIL | VVYLDRAQDL | PLKKGNKEPN |
550:
PMVQLSIQDV | TQESKAVYST | NCPVWEEAFR | FFLQDPQSQE | LDVQVKDDSR |
600:
ALTLGALTLP | LARLLTAPEL | ILDQWFQLSS | SGPNSRLYMK | LVMRILYLDS |
650:
SEICFPTVPG | CPGAWDVDSE | NPQRGSSVDA | PPRPCHTTPD | SQFGTEHVLR |
700:
IHVLEAQDLI | AKDRFLGGLV | KGKSDPYVKL | KLAGRSFRSH | VVREDLNPRW |
750:
NEVFEVIVTS | VPGQELEVEV | FDKDLDKDDF | LGRCKVRLTT | VLNSGFLDEW |
800:
LTLEDVPSGR | LHLRLERLTP | RPTAAELEEV | LQVNSLIQTQ | KSAELAAALL |
850:
SIYMERAEDL | PLRKGTKHLS | PYATLTVGDS | SHKTKTISQT | SAPVWDESAS |
900:
FLIRKPHTES | LELQVRGEGT | GVLGSLSLPL | SELLVADQLC | LDRWFTLSSG |
950:
QGQVLLRAQL | GILVSQHSGV | EAHSHSYSHS | SSSLSEEPEL | SGGPPHITSS |
1000:
APELRQRLTH | VDSPLEAPAG | PLGQVKLTLW | YYSEERKLVS | IVHGCRSLRQ |
1050:
NGRDPPDPYV | SLLLLPDKNR | GTKRRTSQKK | RTLSPEFNER | FEWELPLDEA |
1100:
QRRKLDVSVK | SNSSFMSRER | ELLGKVQLDL | AETDLSQGVA | RWYDLMDNKD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
ELISA Kit for Human E-Syt1
ELISA Kit for Human E-Syt1
ELISA Kit for Human E-Syt1
CLIA Kit for Human E-Syt1
CLIA Kit for Human E-Syt1
CLIA Kit for Human E-Syt1
Polyclonal Antibody for Human E-Syt1
Polyclonal Antibody for Human E-Syt1
Polyclonal Antibody for Human E-Syt1
Monoclonal Antibody for Human E-Syt1
Monoclonal Antibody for Human E-Syt1
Monoclonal Antibody for Human E-Syt1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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Kidney .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 379-1104 (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-963 AND SER-1034;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-820 AND SER-963;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
15.
"PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins."
Giordano F.
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Cell153:1494-1509(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;TOPOLOGY;LIPID-BINDING;MUTAGENESIS OF ASP-663; ASP-675 AND 722-ASP--ASP-729;INTERACTION WITH ESYT2 AND ESYT3
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF ASP-406 AND ASP-724