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Index > Protein center > Ethe1(Gene name) > Mouse
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  • Ethe1 (Gene name),
  • Protein ETHE1, mitochondrial (Protein name ),  ETHE1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ethe1(Hsco);
    Protein name:
    Protein ETHE1, mitochondrial;
    Alternative:
    Hepatoma subtracted clone one protein;Ethylmalonic encephalopathy protein 1 homolog;Sulfur dioxygenase ETHE1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with RELA.
    Function:
    Probably plays an important role in metabolic homeostasis in mitochondria. May function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. Suppresses p53-induced apoptosis by preventing nuclear localization of RELA.
    Subcellular Location:
    Cytoplasm Nucleus Mitochondrion matrix
    Protein Attributes:
    Sequence length:
    254
    Sequence:
    50:
    MASAVVRVAG | RRLSQQSASG | APVLLRQMFE | PKSCTYTYLL | GDRESREAVL | 
    100:
    IDPVLETAHR | DAQLIKELGL | KLLYAVNTHC | HADHITGTGV | LRSLLPGCQS | 
    150:
    VISRLSGAQA | DLHIGEGDSI | RFGRFALETR | ASPGHTPGCV | TFVLNDQSMA | 
    200:
    FTGDALLIRG | CGRTDFQQGC | AKTLYHSVHE | KIFTLPGNCL | IYPAHDYHGL | 
    250:
    TVSTVEEERT | LNPRLTLSCE | EFIKVMDNLN | LPKPQQIDIA | VPANMRCGVQ | 
    254:
    TPPS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Protein ETHE1, mitochondrial
    ELISA Kit for Mouse Protein ETHE1, mitochondrial
    ELISA Kit for Mouse Protein ETHE1, mitochondrial
    CLIA Kit for Mouse Protein ETHE1, mitochondrial
    CLIA Kit for Mouse Protein ETHE1, mitochondrial
    CLIA Kit for Mouse Protein ETHE1, mitochondrial
    Polyclonal Antibody for Mouse Protein ETHE1, mitochondrial
    Polyclonal Antibody for Mouse Protein ETHE1, mitochondrial
    Polyclonal Antibody for Mouse Protein ETHE1, mitochondrial
    Monoclonal Antibody for Mouse Protein ETHE1, mitochondrial
    Monoclonal Antibody for Mouse Protein ETHE1, mitochondrial
    Monoclonal Antibody for Mouse Protein ETHE1, mitochondrial
    Protein for Mouse Protein ETHE1, mitochondrial
    Protein for Mouse Protein ETHE1, mitochondrial
    Protein for Mouse Protein ETHE1, mitochondrial

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    Precision
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    Linearity
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    References
    1. 1.
      "Expression of HSCO in hepatomas."
      Fujita J. , Higashitsuji H. , Higashitsuji H.
      Submitted (2000-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Kidney.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Colon.
      tissue: Kidney.
      tissue: Mammary tumor.
    4. 4.
      "Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy."
      Tiranti V. , Viscomi C. , Hildebrandt T. , Di Meo I. , Mineri R. , Tiveron C. , Levitt M.D. , Prelle A. , Fagiolari G. , Rimoldi M. , Zeviani M.
      Nat. Med.15:200-205(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    5. 5.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-32 AND LYS-172;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    6. 6.
      "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
      Rardin M.J. , Newman J.C. , Held J.M. , Cusack M.P. , Sorensen D.J. , Li B. , Schilling B. , Mooney S.D. , Kahn C.R. , Verdin E. , Gibson B.W.
      Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-32; LYS-66 AND LYS-172;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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