Gene name:
EFTUD1 (EFL1;FAM42A) ;
Protein name:
Elongation factor Tu GTP-binding domain-containing protein 1 ;
Alternative:
Protein FAM42A ;Elongation factor-like 1 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Associates with the 60S ribosomal subunit.
Function:
Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
Subcellular Location:
N/A
Protein Attributes:
50:
MVLNSLDKMI | QLQKNTANIR | NICVLAHVDH | GKTTLADCLI | SSNGIISSRL |
100:
AGKLRYMDSR | EDEQIRGITM | KSSAISLHYA | TGNEEYLINL | IDSPGHVDFS |
150:
SEVSTAVRIC | DGCIIVVDAV | EGVCPQTQAV | LRQAWLENIR | PVLVINKIDR |
200:
LIVELKFTPQ | EAYSHLKNIL | EQINALTGTL | FTSKVLEERA | ERETESQVNP |
250:
NSEQGEQVYD | WSTGLEDTDD | SHLYFSPEQG | NVVFTSAIDG | WGFGIEHFAR |
300:
IYSQKIGIKK | EVLMKTLWGD | YYINMKAKKI | MKGDQAKGKK | PLFVQLILEN |
350:
IWSLYDAVLK | KDKDKIDKIV | TSLGLKIGAR | EARHSDPKVQ | INAICSQWLP |
400:
ISHAVLAMVC | QKLPSPLDIT | AERVERLMCT | GSQTFDSFPP | ETQALKAAFM |
450:
KCGSEDTAPV | IIFVSKMFAV | DAKALPQNKP | RPLTQEEIAQ | RRERARQRHA |
500:
EKLAAAQGQA | PLEPTQDGSA | IETCPKGEEP | RGDEQQVESM | TPKPVLQEEN |
550:
NQESFIAFAR | VFSGVARRGK | KIFVLGPKYS | PLEFLRRVPL | GFSAPPDGLP |
600:
QVPHMAYCAL | ENLYLLMGRE | LEYLEEVPPG | NVLGIGGLQD | FVLKSATLCS |
650:
LPSCPPFIPL | NFEATPIVRV | AVEPKHPSEM | PQLVKGMKLL | NQADPCVQIL |
700:
IQETGEHVLV | TAGEVHLQRC | LDDLKERFAK | IHISVSEPII | PFRETITKPP |
750:
KVDMVNEEIG | KQQKVAVIHQ | MKEDQSKIPE | GIQVDSDGLI | TITTPNKLAT |
800:
LSVRAMPLPE | EVTQILEENS | DLIRSMEQLT | SSLNEGENTH | MIHQKTQEKI |
850:
WEFKGKLEQH | LTGRRWRNIV | DQIWSFGPRK | CGPNILVNKS | EDFQNSVWTG |
900:
PADKASKEAS | RYRDLGNSIV | SGFQLATLSG | PMCEEPLMGV | CFVLEKWDLS |
950:
KFEEQGASDL | AKEGQEENET | CSGGNENQEL | QDGCSEAFEK | RTSQKGESPL |
1000:
TDCYGPFSGQ | LIATMKEACR | YALQVKPQRL | MAAMYTCDIM | ATGDVLGRVY |
1050:
AVLSKREGRV | LQEEMKEGTD | MFIIKAVLPV | AESFGFADEI | RKRTSGLASP |
1100:
QLVFSHWEII | PSDPFWVPTT | EEEYLHFGEK | ADSENQARKY | MNAVRKRKGL |
1120:
YVEEKIVEHA | EKQRTLSKNK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Elongation factor Tu GTP-binding domain-containing protein 1
ELISA Kit for Human Elongation factor Tu GTP-binding domain-containing protein 1
CLIA Kit for Human Elongation factor Tu GTP-binding domain-containing protein 1
CLIA Kit for Human Elongation factor Tu GTP-binding domain-containing protein 1
Polyclonal Antibody for Human Elongation factor Tu GTP-binding domain-containing protein 1
Polyclonal Antibody for Human Elongation factor Tu GTP-binding domain-containing protein 1
Monoclonal Antibody for Human Elongation factor Tu GTP-binding domain-containing protein 1
Monoclonal Antibody for Human Elongation factor Tu GTP-binding domain-containing protein 1
Protein for Human Elongation factor Tu GTP-binding domain-containing protein 1
Protein for Human Elongation factor Tu GTP-binding domain-containing protein 1
R&D Technical Data
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT ASP-478
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Fetal brain .
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