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Index > Protein center > EFTUD1(Gene name) > Human
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  • EFTUD1 (Gene name),
  • Elongation factor Tu GTP-binding domain-containing protein 1 (Protein name ),  ETUD1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    EFTUD1(EFL1;FAM42A);
    Protein name:
    Elongation factor Tu GTP-binding domain-containing protein 1;
    Alternative:
    Protein FAM42A;Elongation factor-like 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Associates with the 60S ribosomal subunit.
    Function:
    Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    1120
    Sequence:
    50:
    MVLNSLDKMI | QLQKNTANIR | NICVLAHVDH | GKTTLADCLI | SSNGIISSRL | 
    100:
    AGKLRYMDSR | EDEQIRGITM | KSSAISLHYA | TGNEEYLINL | IDSPGHVDFS | 
    150:
    SEVSTAVRIC | DGCIIVVDAV | EGVCPQTQAV | LRQAWLENIR | PVLVINKIDR | 
    200:
    LIVELKFTPQ | EAYSHLKNIL | EQINALTGTL | FTSKVLEERA | ERETESQVNP | 
    250:
    NSEQGEQVYD | WSTGLEDTDD | SHLYFSPEQG | NVVFTSAIDG | WGFGIEHFAR | 
    300:
    IYSQKIGIKK | EVLMKTLWGD | YYINMKAKKI | MKGDQAKGKK | PLFVQLILEN | 
    350:
    IWSLYDAVLK | KDKDKIDKIV | TSLGLKIGAR | EARHSDPKVQ | INAICSQWLP | 
    400:
    ISHAVLAMVC | QKLPSPLDIT | AERVERLMCT | GSQTFDSFPP | ETQALKAAFM | 
    450:
    KCGSEDTAPV | IIFVSKMFAV | DAKALPQNKP | RPLTQEEIAQ | RRERARQRHA | 
    500:
    EKLAAAQGQA | PLEPTQDGSA | IETCPKGEEP | RGDEQQVESM | TPKPVLQEEN | 
    550:
    NQESFIAFAR | VFSGVARRGK | KIFVLGPKYS | PLEFLRRVPL | GFSAPPDGLP | 
    600:
    QVPHMAYCAL | ENLYLLMGRE | LEYLEEVPPG | NVLGIGGLQD | FVLKSATLCS | 
    650:
    LPSCPPFIPL | NFEATPIVRV | AVEPKHPSEM | PQLVKGMKLL | NQADPCVQIL | 
    700:
    IQETGEHVLV | TAGEVHLQRC | LDDLKERFAK | IHISVSEPII | PFRETITKPP | 
    750:
    KVDMVNEEIG | KQQKVAVIHQ | MKEDQSKIPE | GIQVDSDGLI | TITTPNKLAT | 
    800:
    LSVRAMPLPE | EVTQILEENS | DLIRSMEQLT | SSLNEGENTH | MIHQKTQEKI | 
    850:
    WEFKGKLEQH | LTGRRWRNIV | DQIWSFGPRK | CGPNILVNKS | EDFQNSVWTG | 
    900:
    PADKASKEAS | RYRDLGNSIV | SGFQLATLSG | PMCEEPLMGV | CFVLEKWDLS | 
    950:
    KFEEQGASDL | AKEGQEENET | CSGGNENQEL | QDGCSEAFEK | RTSQKGESPL | 
    1000:
    TDCYGPFSGQ | LIATMKEACR | YALQVKPQRL | MAAMYTCDIM | ATGDVLGRVY | 
    1050:
    AVLSKREGRV | LQEEMKEGTD | MFIIKAVLPV | AESFGFADEI | RKRTSGLASP | 
    1100:
    QLVFSHWEII | PSDPFWVPTT | EEEYLHFGEK | ADSENQARKY | MNAVRKRKGL | 
    1120:
    YVEEKIVEHA | EKQRTLSKNK | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Elongation factor Tu GTP-binding domain-containing protein 1
    ELISA Kit for Human Elongation factor Tu GTP-binding domain-containing protein 1
    CLIA Kit for Human Elongation factor Tu GTP-binding domain-containing protein 1
    CLIA Kit for Human Elongation factor Tu GTP-binding domain-containing protein 1
    Polyclonal Antibody for Human Elongation factor Tu GTP-binding domain-containing protein 1
    Polyclonal Antibody for Human Elongation factor Tu GTP-binding domain-containing protein 1
    Monoclonal Antibody for Human Elongation factor Tu GTP-binding domain-containing protein 1
    Monoclonal Antibody for Human Elongation factor Tu GTP-binding domain-containing protein 1
    Protein for Human Elongation factor Tu GTP-binding domain-containing protein 1
    Protein for Human Elongation factor Tu GTP-binding domain-containing protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ASP-478
      tissue: Placenta.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT ASP-478
      tissue: Fetal brain.
    3. 4.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-528;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    5. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;MUTAGENESIS OF THR-33 AND HIS-96
    6. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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