ETV6 ELISA Kit for Human(Homo sapiens) | EIAab.comETV6 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > ETV6(Gene name) > Human

ETV6 (Gene name),

Transcription factor ETV6 (Protein name ), ETV6_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ETV6(TEL;TEL1);

Protein name:

Transcription factor ETV6;

Alternative:

ETS-related protein Tel1(Tel);ETS translocation variant 6;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Can form homodimers or heterodimers with TEL2 or FLI1. Interacts with L3MBTL1 and HDAC9.

Function:

Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

452

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

452:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.504765

SMR:

P41212

KEGG:

hsa:2120

MIM:

131440

Pfam:

PF00178

String:

P41212

STRING:

9606.ENSP00000266427

Uniprot:

P41212

FOR

ELISA Kit for Human Transcription factor ETV6

CLIA Kit for Human Transcription factor ETV6

Polyclonal Antibody for Human Transcription factor ETV6

Monoclonal Antibody for Human Transcription factor ETV6

Protein for Human Transcription factor ETV6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation."
Golub T.R. , Barker G.F. , Lovett M. , Gilliland D.G.
Cell77:307-316(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Urinary bladder.
3.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.
5.

"Genomic organization of TEL: the human ETS-variant gene 6."
Baens M. , Peeters P. , Guo C. , Aerssens J. , Marynen P.
Genome Res.6:404-413(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 56-109; 111-336 AND 338-452
6.

"Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia."
Mullighan C.G. , Goorha S. , Radtke I. , Miller C.B. , Coustan-Smith E. , Dalton J.D. , Girtman K. , Mathew S. , Ma J. , Pounds S.B. , Su X. , Pui C.-H. , Relling M.V. , Evans W.E. , Shurtleff S.A. , Downing J.R.
Nature446:758-764(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 56-452;CHROMOSOMAL TRANSLOCATION WITH PAX5
7.

"Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia."
Golub T.R. , Barker G.F. , Bohlander S.K. , Hiebert S.W. , Ward D.C. , Bray-Ward P. , Morgan E. , Raimondi S.C. , Rowley J.D. , Gilliland D.G.
Proc. Natl. Acad. Sci. U.S.A.92:4917-4921(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH AML1
8.

"The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion."
Romana S.P. , Mauchauffe M. , le Coniat M. , Chumakov I. , le Paslier D. , Berger R. , Bernard O.A.
Blood85:3662-3670(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH AML1
9.

"Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13)."
Yagasaki F. , Jinnai I. , Yoshida S. , Yokoyama Y. , Matsuda A. , Kusumoto S. , Kobayashi H. , Terasaki H. , Ohyashiki K. , Asou N. , Murohashi I. , Bessho M. , Hirashima K.
Genes Chromosomes Cancer26:192-202(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH ACSL6
10.

"Fusion of a novel gene, BTL, to ETV6 in acute myeloid leukemias with a t(4;12)(q11-q12;p13)."
Cools J. , Bilhou-Nabera C. , Wlodarska I. , Cabrol C. , Talmant P. , Bernard P. , Hagemeijer A. , Marynen P.
Blood94:1820-1824(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH CHIC2
11.

"Functional regulation of TEL by p38-induced phosphorylation."
Arai H. , Maki K. , Waga K. , Sasaki K. , Nakamura Y. , Imai Y. , Kurokawa M. , Hirai H. , Mitani K.
Biochem. Biophys. Res. Commun.299:116-125(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-22 AND SER-257;MUTAGENESIS OF SER-213; SER-238 AND SER-257
12.

"A novel gene, MDS2, is fused to ETV6/TEL in a t(1;12)(p36.1;p13) in a patient with myelodysplastic syndrome."
Odero M.D. , Vizmanos J.L. , Roman J.P. , Lahortiga I. , Panizo C. , Calasanz M.J. , Zeleznik-Le N.J. , Rowley J.D. , Novo F.J.
Genes Chromosomes Cancer35:11-19(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH MDS2
13.

"Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta."
Apperley J.F. , Gardembas M. , Melo J.V. , Russell-Jones R. , Bain B.J. , Baxter E.J. , Chase A. , Chessells J.M. , Colombat M. , Dearden C.E. , Dimitrijevic S. , Mahon F.-X. , Marin D. , Nikolova Z. , Olavarria E. , Silberman S. , Schultheis B. , Cross N.C.P. , more...
N. Engl. J. Med.347:481-487(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH PDGFRB
14.

"The human L(3)MBT Polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)."
Boccuni P. , MacGrogan D. , Scandura J.M. , Nimer S.D.
J. Biol. Chem.278:15412-15420(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH L3MBTL1
15.

"The histone deacetylase 9 gene encodes multiple protein isoforms."
Petrie K. , Guidez F. , Howell L. , Healy L. , Waxman S. , Greaves M. , Zelent A.
J. Biol. Chem.278:16059-16072(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HDAC9
16.

"Somatic heterozygous mutations in ETV6 (TEL) and frequent absence of ETV6 protein in acute myeloid leukemia."
Barjesteh van Waalwijk van Doorn-Khosrovani S. , Spensberger D. , de Knegt Y. , Tang M. , Loewenberg B. , Delwel R.
Oncogene24:4129-4137(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN AML;VARIANT GLY-344 INS;CHARACTERIZATION OF VARIANT GLY-344 INS
17.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-22;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
18.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-18 AND SER-22;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
19.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2; LYS-11 AND LYS-302;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
20.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-22;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
21.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-22 AND SER-213;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
22.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
23.

"Solution structure of ets domain transcriptional factor ETV6 protein."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-12) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 338-442

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