FAM175A ELISA Kit for Bovine(Bos taurus) | EIAab.comFAM175A ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > FAM175A(Gene name) > Bovine

FAM175A (Gene name),

BRCA1-A complex subunit Abraxas (Protein name ), F175A_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FAM175A(ABRA1;CCDC98);

Protein name:

BRCA1-A complex subunit Abraxas;

Alternative:

Protein FAM175A;Coiled-coil domain-containing protein 98;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Component of the BRCA1-A complex, at least composed of the BRCA1, BARD1, UIMC1/RAP80, FAM175A/Abraxas, BRCC3/BRCC36, BRE/BRCC45 and BABAM1/NBA1. In the complex, interacts directly with UIMC1/RAP80, BRCC3/BRCC36 and BRE/BRCC45. Interacts directly (when phosphorylated at Ser-407) with BRCA1. Binds polyubiquitin.

Function:

Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.

Subcellular Location:

Nucleus Localizes at sites of DNA damage at double-strand breaks (DSBs).

Protein Attributes:

Sequence length:

410

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

410:

SGEYPQSPTF |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Bt.32406

String:

Q5E9P1

KEGG:

bta:504796

Uniprot:

Q5E9P1

FOR

ELISA Kit for Bovine BRCA1-A complex subunit Abraxas

CLIA Kit for Bovine BRCA1-A complex subunit Abraxas

Polyclonal Antibody for Bovine BRCA1-A complex subunit Abraxas

Monoclonal Antibody for Bovine BRCA1-A complex subunit Abraxas

Protein for Bovine BRCA1-A complex subunit Abraxas

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Characterization of 954 bovine full-CDS cDNA sequences."
Harhay G.P. , Sonstegard T.S. , Keele J.W. , Heaton M.P. , Clawson M.L. , Snelling W.M. , Wiedmann R.T. , Van Tassell C.P. , Smith T.P.L.
BMC Genomics6:166-166(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
2.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2006-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Fetal skin.

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