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Index > Protein center > FAM175A(Gene name) > Chicken
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  • FAM175A (Gene name),
  • BRCA1-A complex subunit Abraxas (Protein name ),  F175A_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FAM175A(RCJMB04_33o10;ABRA1;CCDC98);
    Protein name:
    BRCA1-A complex subunit Abraxas;
    Alternative:
    Protein FAM175A;Coiled-coil domain-containing protein 98;
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Component of the BRCA1-A complex. Component of the BRISC complex. Interacts directly (when phosphorylated at Ser-402) with BRCA1.
    Function:
    Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.
    Subcellular Location:
    Nucleus Localizes at sites of DNA damage at double-strand breaks (DSBs).
    Protein Attributes:
    Sequence length:
    405
    Sequence:
    50:
    MEGESTSALL | SGFVFGALAF | QHLSTDSDTE | GFLLGDVKGE | AKNSITDSQM | 
    100:
    DDVEVVYTID | IQKHIPCYQL | FSFYNSAGEL | NEPALKKILS | GRKKSVIGWY | 
    150:
    KFRRNTDQIM | TFRERLLHKN | LQSHLSNQGL | VFLLLTSSVM | TESCSTYRLE | 
    200:
    HALHRPQEGL | FQKVPLVVTN | LGMAEQQGYR | TVSGSCASSG | FVRAVKQHRS | 
    250:
    EFFYEDGSLQ | EVHKINEMYA | TLQEELKKMC | SDVEVSERSV | EKLLTEVSQL | 
    300:
    KEEINRKKQH | KISSGGNKDQ | LEEPKENVLL | CQALRTFFPS | SDLQTCIVSF | 
    350:
    KGRISKNCCK | IDHNINIMDK | LTLMVEERDF | TEAETKLVTK | RKVRVTTTGP | 
    400:
    KSLKKLRSLQ | LDQELHQDEE | DCNQETKLAL | SSAETDEEAL | ENPKDTNEYS | 
    405:
    YSPTF
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken BRCA1-A complex subunit Abraxas
    ELISA Kit for Chicken BRCA1-A complex subunit Abraxas
    ELISA Kit for Chicken BRCA1-A complex subunit Abraxas
    ELISA Kit for Chicken BRCA1-A complex subunit Abraxas
    ELISA Kit for Chicken BRCA1-A complex subunit Abraxas
    CLIA Kit for Chicken BRCA1-A complex subunit Abraxas
    CLIA Kit for Chicken BRCA1-A complex subunit Abraxas
    CLIA Kit for Chicken BRCA1-A complex subunit Abraxas
    CLIA Kit for Chicken BRCA1-A complex subunit Abraxas
    CLIA Kit for Chicken BRCA1-A complex subunit Abraxas
    Polyclonal Antibody for Chicken BRCA1-A complex subunit Abraxas
    Polyclonal Antibody for Chicken BRCA1-A complex subunit Abraxas
    Polyclonal Antibody for Chicken BRCA1-A complex subunit Abraxas
    Polyclonal Antibody for Chicken BRCA1-A complex subunit Abraxas
    Polyclonal Antibody for Chicken BRCA1-A complex subunit Abraxas
    Monoclonal Antibody for Chicken BRCA1-A complex subunit Abraxas
    Monoclonal Antibody for Chicken BRCA1-A complex subunit Abraxas
    Monoclonal Antibody for Chicken BRCA1-A complex subunit Abraxas
    Monoclonal Antibody for Chicken BRCA1-A complex subunit Abraxas
    Monoclonal Antibody for Chicken BRCA1-A complex subunit Abraxas
    Protein for Chicken BRCA1-A complex subunit Abraxas
    Protein for Chicken BRCA1-A complex subunit Abraxas
    Protein for Chicken BRCA1-A complex subunit Abraxas
    Protein for Chicken BRCA1-A complex subunit Abraxas
    Protein for Chicken BRCA1-A complex subunit Abraxas

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: CB.
      tissue: Bursa of Fabricius.
    2. 2.
      "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution."
      Hillier L.W. , Miller W. , Birney E. , Warren W. , Hardison R.C. , Ponting C.P. , Bork P. , Burt D.W. , Groenen M.A.M. , Delany M.E. , Dodgson J.B. , Chinwalla A.T. , Cliften P.F. , Clifton S.W. , Delehaunty K.D. , Fronick C. , Fulton R.S. , Graves T.A. , more...
      Nature432:695-716(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Red jungle fowl.
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