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Index > Protein center > F5(Gene name) > Bovine
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  • F5 (Gene name),
  • Coagulation factor V (Protein name ),  FA5_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    F5;
    Protein name:
    Coagulation factor V;
    Alternative:
    Activated protein C cofactor;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Factor Va, the activated form of factor V, is composed of a heavy chain and a light chain, non-covalently bound. The interaction between the two chains is calcium-dependent.
    Function:
    Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    2211
    Sequence:
    50:
    MFLACPGFWV | LVVLGSSWAG | WGNLGAEAAK | LRQFYVAAQS | IRWNYRPEST | 
    100:
    HLSSKPFETS | FKKIVYREYE | AYFQKEKPQS | RTSGLLGPTL | YAEVGDIMKV | 
    150:
    HFKNKAHKPL | SIHAQGIKYS | KFSEGASYSD | HTLPMEKMDD | AVAPGQEYTY | 
    200:
    EWIISEHSGP | THDDPPCLTH | IYYSYVNLVE | DFNSGLIGPL | LICKKGTLTE | 
    250:
    DGTQKMFEKQ | HVLMFAVFDE | SKSWNQTSSL | MYTVNGYVNG | TMPDITVCAH | 
    300:
    DHISWHLIGM | SSGPELFSIH | FNGQVLEQNH | HKISAITLVS | ATSTTANMTV | 
    350:
    SPEGRWTIAS | LIPRHFQAGM | QAYIDIKNCA | KKTRNPKKLT | RDQRRHIKRW | 
    400:
    EYFIAAEEVI | WDYAPIIPAN | MDKKYRSLHL | DNFSNRIGKH | YKKVVYKQYQ | 
    450:
    DDSFTKRLED | PSSEGDGILG | PIIRAQVRDT | LKIVFKNMAS | RSYSIYPHGV | 
    500:
    TFSPYDNEVN | SSSTSGSNTM | IRAVRPGETY | TYKWNILESD | EPTENDAQCL | 
    550:
    TRPYYSNVDI | TRDLASGLIG | LLLICKSRSL | DRRGIQRAAD | IEQQAVFAVF | 
    600:
    DENKSWYIED | NIYKFCENPE | KVKRDDPKFY | ESNIMSNFTL | PAINGYVPES | 
    650:
    IPILGFCFDD | TVQWHFCSVG | TQNDILTIHF | TGHSFIYGKR | HEDTLTLFPM | 
    700:
    QGESVTVTMD | NVGTWMLTTM | NSNPRSKKLR | LRFRDAKCIR | NDDDDSYEII | 
    750:
    YEPSGSTAMT | TKKIHDSSEI | EDENDADSDY | QDELALILGL | RSFRNSSLNQ | 
    800:
    EKDELNLTAL | ALEKDSEFIP | PSANRSLDSN | SSSRSHVSRL | IAKNFAESLK | 
    850:
    TLLHLEAPAA | GSPLEHAGLD | KNSALNPPMA | EHSSPYSEDP | REDHPLSDVT | 
    900:
    GVSLLPFGTG | FKNRKPAKHQ | RFQVGRGQAA | KHKFSQTRFP | AHKTRTRLSQ | 
    950:
    DNSSSSRMGP | WEDIPSDLLL | LQQKDPYKIL | NGEWHLVSEK | GSYEIIQDAN | 
    1000:
    ENKTVNKLPN | SPQNDSRTWG | ENIPFKNSHG | KQSGHPTFLV | TRRKPLQDRQ | 
    1050:
    DRRNSRLKEG | LPLIRTRRKK | KEEKPAYHVP | LSPRSFHPLR | GEVNASFSDR | 
    1100:
    RHNHSLLLHA | SNETSLSIDL | NQTFPSMNLS | LAASLPDHDQ | TSPNDTTSQT | 
    1150:
    SSPPDLYPTV | SPEEHYQIFP | IQDSDPTHST | TAPSNRSPDP | THSTTAPSNR | 
    1200:
    SPPTQPSQIP | NYDLRNRAIP | TDVSQIFPSL | ELEVWQTATS | LDLSQPSISP | 
    1250:
    DLGQMALSPD | PGQESLSPDL | GQTSLSPDLS | QESLSPDLGQ | TALSPDPSQE | 
    1300:
    SLSPDLGQTA | LSPDPSQESL | SPDLGQTALS | PDPGQESLSP | DLGQTSLSPD | 
    1350:
    LSQESLSPDL | GQTALSPDPS | QESLSPDLGQ | TALSPDPSQE | SLSPDLGQTS | 
    1400:
    LSPDLGQESL | SPDLGQTALS | PDPSQESLSP | DLGQTSLSPD | LGQESLSPDL | 
    1450:
    GQTALSPDLS | QESLSPDLGQ | TPLSPDLSLE | SLSPDLSQLD | LKQTSPPLDL | 
    1500:
    NQTSHTSESS | QSLPLPEFGQ | TFPNADIGQM | PSPPPDSTLN | NTFIPEEFNP | 
    1550:
    LVVVGLSRDD | GDYIEIIPRQ | KEESSEEDYG | EFEFVAYNDP | YQTDLRTDIN | 
    1600:
    SSRNPDNIAA | WYLRSNTGNR | KYYYIAAEEI | SWDYSKFVQS | DDVDYVPEDT | 
    1650:
    VYKKVVFRKY | LDSTFTKLDP | QGEYEEHLGI | LGPVIRAEVD | DVIQVRFKNL | 
    1700:
    ASRPYSLHAH | GLSYEKSSEG | KTYEDDSPEW | FKEDNAIQPN | KTYTYVWHAT | 
    1750:
    TRSGPENPGS | ACRAWAYYSA | VNPEKDIHSG | LIGPLLICRK | GTLDKETNMP | 
    1800:
    VDMREFVLLF | MVFDEKKSWY | YDKKPTRSWR | RASSEVKNSH | EFHAINGMIY | 
    1850:
    NLPGLRMYEQ | EWVRLHLLNL | GGSRDIHVVH | FHGQTLLENG | TQQHQLGVWP | 
    1900:
    LLPGSFKTLE | MKASKPGWWL | LDTEVGEIQR | AGMQTPFLIV | DRECKMPMGL | 
    1950:
    STGLIADSQI | QASEFWGYWE | PKLARLNNGG | SYNAWIAEKL | STEFNPEPWI | 
    2000:
    QVDMQKEVLL | TGIQTQGAKH | YLKPYYTTEF | CVAYSLDRKN | WRIFKGNSTR | 
    2050:
    NVMYFGGNSD | ASTIKENQID | PPVVARYIRI | SPTGSYNKPA | LRLELQGCEV | 
    2100:
    NGCSTPLGME | SGKIENKQIT | ASSFKKSWWG | NYWEPFLARL | NAQGRVNAWQ | 
    2150:
    AKANNNNQWL | QIDLLKIKKI | TAIVTQGCKS | LSSEMYVKSY | TIHYSDQGTD | 
    2200:
    WKPYREKSSM | VDKIFEGNNN | VRGHVKNFFN | PPIISRFIRI | IPKTWNQSIA | 
    2211:
    LRLELFGCDM | Y
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Coagulation factor V
    Cat.:
    E0728p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Coagulation factor V
    Cat.:
    E0728h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Coagulation factor V
    Cat.:
    E0728b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine Coagulation factor V
    Cat.:
    E0728m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor V
    Cat.:
    U0728p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine Coagulation factor V
    Cat.:
    U0728b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor V
    Cat.:
    U0728h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor V
    Cat.:
    U0728m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Coagulation factor V
    Polyclonal Antibody for Bovine Coagulation factor V
    Polyclonal Antibody for Bovine Coagulation factor V
    Cat.:
    P0728Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Coagulation factor V
    Cat.:
    P0728Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Coagulation factor V
    Monoclonal Antibody for Bovine Coagulation factor V
    Monoclonal Antibody for Bovine Coagulation factor V
    Monoclonal Antibody for Bovine Coagulation factor V
    Protein for Bovine Coagulation factor V
    Protein for Bovine Coagulation factor V
    Protein for Bovine Coagulation factor V
    Protein for Bovine Coagulation factor V

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    References
    1. 1.
      "The complete cDNA sequence of bovine coagulation factor V."
      Guinto E.R. , Esmon C.T. , Mann K.G. , Macgillivray R.T.
      J. Biol. Chem.267:2971-2978(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    2. 2.
      "Determination of the disulfide bridges in factor Va heavy chain."
      Xue J. , Kalafatis M. , Silveira J.R. , Kung C. , Mann K.G.
      Biochemistry33:13109-13116(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS
    3. 3.
      "The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function."
      Adams T.E. , Hockin M.F. , Mann K.G. , Everse S.J.
      Proc. Natl. Acad. Sci. U.S.A.101:8918-8923(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 29-2211;GLYCOSYLATION AT ASN-225 AND ASN-239;DISULFIDE BONDS;METAL-BINDING SITES
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